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Idebenone Regulates Aβ and LPS-Induced Neurogliosis and Cognitive Function Through Inhibition of NLRP3 Inflammasome/IL-1β Axis Activation

Idebenone is an analogue of coenzyme Q10, an electron donor in the mitochondrial electron transport chain, and thus may function as an antioxidant to facilitate mitochondrial function. However, whether idebenone modulates LPS- and Aβ-mediated neuroinflammatory responses and cognitive function in viv...

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Detalles Bibliográficos
Autores principales:	Lee, Hyun-ju, Park, Jin-Hee, Hoe, Hyang-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866241/ https://www.ncbi.nlm.nih.gov/pubmed/35222363 http://dx.doi.org/10.3389/fimmu.2022.749336

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