Cargando…
The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up
PURPOSE: Bariatric surgery (BS) induces a significant and sustained weight loss in patients with severe obesity (SO). Nevertheless, apart from significantly reducing body fat, fat-free mass (FFM) might also be lost. At present, there is little and controversial data in the literature regarding the i...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866285/ https://www.ncbi.nlm.nih.gov/pubmed/34846686 http://dx.doi.org/10.1007/s11695-021-05815-x |
_version_ | 1784655800492359680 |
---|---|
author | Martínez, Marta Comas Meli, Enzamaria Fidilio Candia, Fiorella Palmas Filippi, Francesca Vilallonga, Ramon Cordero, Efrain Hernández, Irene Eguinoa, Alba Zabalegui Burgos, Rosa Vila, Anna Simó, Rafael Ciudin, Andreea |
author_facet | Martínez, Marta Comas Meli, Enzamaria Fidilio Candia, Fiorella Palmas Filippi, Francesca Vilallonga, Ramon Cordero, Efrain Hernández, Irene Eguinoa, Alba Zabalegui Burgos, Rosa Vila, Anna Simó, Rafael Ciudin, Andreea |
author_sort | Martínez, Marta Comas |
collection | PubMed |
description | PURPOSE: Bariatric surgery (BS) induces a significant and sustained weight loss in patients with severe obesity (SO). Nevertheless, apart from significantly reducing body fat, fat-free mass (FFM) might also be lost. At present, there is little and controversial data in the literature regarding the impact of BS on FFM. In recent years, bioimpedance (BIA) has emerged as a reliable test to assess body composition easily to use in the daily clinical practice. On the bases, the aim of the present study is to evaluate the impact of BS on the FFM, evaluated by means of BIA. MATERIAL AND METHODS: This is a prospective, observational study, including consecutive patients with SO that underwent BS between February 2018 and February 2019 at our center. At baseline, 1, 6, 12, and 24 months after the BS, all the patients underwent complete medical history, physical and anthropometric evaluation, and body composition assessment by means of BIA (using Bodystat QuadScan4000®). RESULTS: Eighty-five patients with SO were recruited, 72.9% females, aged 45.54 ± 9.98 years, pre-BS BMI 43.87 ± 6.52 kg/m(2). FFM significantly decreased continuously after BS at all timepoints. The loss of FFM 24 months post-BS accounted for approximately 21.71 ± 13.9% of the total weight loss, and was independent of BS technique or protein metabolism. Pre-BS HOMA-IR and FFM were independent predictors of FFM at 24 months. CONCLUSIONS: Significant and early loss of FFM in patients with SO that undergo BS was seen, not related to protein metabolism parameters or the BS technique used, suggesting an independent mechanism. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-8866285 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-88662852022-03-02 The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up Martínez, Marta Comas Meli, Enzamaria Fidilio Candia, Fiorella Palmas Filippi, Francesca Vilallonga, Ramon Cordero, Efrain Hernández, Irene Eguinoa, Alba Zabalegui Burgos, Rosa Vila, Anna Simó, Rafael Ciudin, Andreea Obes Surg Original Contributions PURPOSE: Bariatric surgery (BS) induces a significant and sustained weight loss in patients with severe obesity (SO). Nevertheless, apart from significantly reducing body fat, fat-free mass (FFM) might also be lost. At present, there is little and controversial data in the literature regarding the impact of BS on FFM. In recent years, bioimpedance (BIA) has emerged as a reliable test to assess body composition easily to use in the daily clinical practice. On the bases, the aim of the present study is to evaluate the impact of BS on the FFM, evaluated by means of BIA. MATERIAL AND METHODS: This is a prospective, observational study, including consecutive patients with SO that underwent BS between February 2018 and February 2019 at our center. At baseline, 1, 6, 12, and 24 months after the BS, all the patients underwent complete medical history, physical and anthropometric evaluation, and body composition assessment by means of BIA (using Bodystat QuadScan4000®). RESULTS: Eighty-five patients with SO were recruited, 72.9% females, aged 45.54 ± 9.98 years, pre-BS BMI 43.87 ± 6.52 kg/m(2). FFM significantly decreased continuously after BS at all timepoints. The loss of FFM 24 months post-BS accounted for approximately 21.71 ± 13.9% of the total weight loss, and was independent of BS technique or protein metabolism. Pre-BS HOMA-IR and FFM were independent predictors of FFM at 24 months. CONCLUSIONS: Significant and early loss of FFM in patients with SO that undergo BS was seen, not related to protein metabolism parameters or the BS technique used, suggesting an independent mechanism. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2021-11-30 2022 /pmc/articles/PMC8866285/ /pubmed/34846686 http://dx.doi.org/10.1007/s11695-021-05815-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Contributions Martínez, Marta Comas Meli, Enzamaria Fidilio Candia, Fiorella Palmas Filippi, Francesca Vilallonga, Ramon Cordero, Efrain Hernández, Irene Eguinoa, Alba Zabalegui Burgos, Rosa Vila, Anna Simó, Rafael Ciudin, Andreea The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up |
title | The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up |
title_full | The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up |
title_fullStr | The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up |
title_full_unstemmed | The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up |
title_short | The Impact of Bariatric Surgery on the Muscle Mass in Patients with Obesity: 2-Year Follow-up |
title_sort | impact of bariatric surgery on the muscle mass in patients with obesity: 2-year follow-up |
topic | Original Contributions |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866285/ https://www.ncbi.nlm.nih.gov/pubmed/34846686 http://dx.doi.org/10.1007/s11695-021-05815-x |
work_keys_str_mv | AT martinezmartacomas theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT melienzamariafidilio theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT candiafiorellapalmas theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT filippifrancesca theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT vilallongaramon theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT corderoefrain theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT hernandezirene theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT eguinoaalbazabalegui theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT burgosrosa theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT vilaanna theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT simorafael theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT ciudinandreea theimpactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT martinezmartacomas impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT melienzamariafidilio impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT candiafiorellapalmas impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT filippifrancesca impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT vilallongaramon impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT corderoefrain impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT hernandezirene impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT eguinoaalbazabalegui impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT burgosrosa impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT vilaanna impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT simorafael impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup AT ciudinandreea impactofbariatricsurgeryonthemusclemassinpatientswithobesity2yearfollowup |