PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer

Glycine N-Methyltransferase (GNMT) is a metabolic enzyme that integrates metabolism and epigenetic regulation. The product of GNMT, sarcosine, has been proposed as a prostate cancer biomarker. This enzyme is predominantly expressed in the liver, brain, pancreas, and prostate tissue, where it exhibit...

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Detalles Bibliográficos
Autores principales: Zabala-Letona, Amaia, Arruabarrena-Aristorena, Amaia, Fernandez-Ruiz, Sonia, Viera, Cristina, Carlevaris, Onintza, Ercilla, Amaia, Mendizabal, Isabel, Martin, Teresa, Macchia, Alice, Camacho, Laura, Pujana-Vaquerizo, Mikel, Sanchez-Mosquera, Pilar, Torrano, Verónica, Martin-Martin, Natalia, Zuniga-Garcia, Patricia, Castillo-Martin, Mireia, Ugalde-Olano, Aitziber, Loizaga-Iriarte, Ana, Unda, Miguel, Mato, Jose M., Berra, Edurne, Martinez-Chantar, Maria L., Carracedo, Arkaitz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866399/
https://www.ncbi.nlm.nih.gov/pubmed/35197445
http://dx.doi.org/10.1038/s41389-022-00382-x

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