Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis

Acral melanoma, the most common melanoma subtype among non-White individuals, is associated with poor prognosis. However, its key molecular drivers remain obscure. Here, we perform integrative genomic and clinical profiling of acral melanomas from 104 patients treated in North America (n = 37) or C...

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Detalles Bibliográficos
Autores principales: Farshidfar, Farshad, Rhrissorrakrai, Kahn, Levovitz, Chaya, Peng, Cong, Knight, James, Bacchiocchi, Antonella, Su, Juan, Yin, Mingzhu, Sznol, Mario, Ariyan, Stephan, Clune, James, Olino, Kelly, Parida, Laxmi, Nikolaus, Joerg, Zhang, Meiling, Zhao, Shuang, Wang, Yan, Huang, Gang, Wan, Miaojian, Li, Xianan, Cao, Jian, Yan, Qin, Chen, Xiang, Newman, Aaron M., Halaban, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866401/
https://www.ncbi.nlm.nih.gov/pubmed/35197475
http://dx.doi.org/10.1038/s41467-022-28566-4

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