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Effects of microRNA-298 on APP and BACE1 translation differ according to cell type and 3′-UTR variation

Alzheimer’s disease (AD) is marked by neurofibrillary tangles and senile plaques composed of amyloid β (Aβ) peptides. However, specific contributions of different cell types to Aβ deposition remain unknown. Non-coding microRNAs (miRNA) play important roles in AD by regulating translation of major as...

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Detalles Bibliográficos
Autores principales:	Wang, Ruizhi, Lahiri, Debomoy K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866491/ https://www.ncbi.nlm.nih.gov/pubmed/35197498 http://dx.doi.org/10.1038/s41598-022-05164-4

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