Duchenne Muscular Dystrophy Patients: Troponin Leak in Asymptomatic and Implications for Drug Toxicity Studies

BACKGROUND: Cardiomyopathy is the leading cause of death in Duchenne Muscular Dystrophy (DMD), but studies suggest heart failure biomarkers correlate poorly with cardiomyopathy severity. DMD clinical trials have used troponin I (cTnI) as a biomarker of toxicity but it is unclear if asymptomatic DMD...

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Detalles Bibliográficos
Autores principales: Sheybani, Aryaz, Crum, Kim, Raucci, Frank J, Burnette, William B, Markham, Larry W, Soslow, Jonathan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866537/
https://www.ncbi.nlm.nih.gov/pubmed/34429516
http://dx.doi.org/10.1038/s41390-021-01682-5

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