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The Global Status and Trends of Enteropeptidase: A Bibliometric Study

BACKGROUND: Enteropeptidase (EP) is a type II transmembrane serine protease and a physiological activator of trypsinogen. Extensive studies related to EP have been conducted to date. However, no bibliometric analysis has systematically investigated this theme. Our study aimed to visualize the curren...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoli, Yin, Hua, Peng, Lisi, Zhang, Deyu, Li, Keliang, Cui, Fang, Xia, Chuanchao, Huang, Haojie, Li, Zhaoshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866687/
https://www.ncbi.nlm.nih.gov/pubmed/35223895
http://dx.doi.org/10.3389/fmed.2022.779722
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author Yang, Xiaoli
Yin, Hua
Peng, Lisi
Zhang, Deyu
Li, Keliang
Cui, Fang
Xia, Chuanchao
Huang, Haojie
Li, Zhaoshen
author_facet Yang, Xiaoli
Yin, Hua
Peng, Lisi
Zhang, Deyu
Li, Keliang
Cui, Fang
Xia, Chuanchao
Huang, Haojie
Li, Zhaoshen
author_sort Yang, Xiaoli
collection PubMed
description BACKGROUND: Enteropeptidase (EP) is a type II transmembrane serine protease and a physiological activator of trypsinogen. Extensive studies related to EP have been conducted to date. However, no bibliometric analysis has systematically investigated this theme. Our study aimed to visualize the current landscape and frontier trends of scientific achievements on EP, provide an overview of the past 120 years and insights for researchers and clinicians to facilitate future collaborative research and clinical intervention. METHODS: Quantitative analysis of publications relating to EP from 1900 to 2020 was interpreted and graphed through the Science Citation Index Expanded of Web of Science Core Collection (limited to SCIE). Microsoft office 2019, GraphPad Prism 8, VOSviewer, and R-bibliometrix were used to conduct the bibliometric analysis. RESULTS: From 1900 to 2020, a total of 1,034 publications were retrieved. The USA had the largest number of publications, making the greatest contribution to the topic (n = 260, 25.15%). Active collaborations between countries/regions were also enrolled. Grant and Hermontaylor were perhaps the most impactful researchers in the landscape of EP. Protein Expression and Purification and the Journal of Biological Chemistry were the most prevalent (79/1,034, 7.64%) and cited journals (n = 2,626), respectively. Using the top 15 citations and co-citations achievements clarified the theoretical basis of the EP research field. Important topics mainly include the structure of EP, the affective factors for activating substrates by EP, EP-related disorders, and inhibitors of EP. CONCLUSION: Based on the bibliometric analysis, we have gained a comprehensive analysis of the global status and research frontiers of studies investigating EP, which provides some guidance and reference for researchers and clinicians engaged in EP research.
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spelling pubmed-88666872022-02-25 The Global Status and Trends of Enteropeptidase: A Bibliometric Study Yang, Xiaoli Yin, Hua Peng, Lisi Zhang, Deyu Li, Keliang Cui, Fang Xia, Chuanchao Huang, Haojie Li, Zhaoshen Front Med (Lausanne) Medicine BACKGROUND: Enteropeptidase (EP) is a type II transmembrane serine protease and a physiological activator of trypsinogen. Extensive studies related to EP have been conducted to date. However, no bibliometric analysis has systematically investigated this theme. Our study aimed to visualize the current landscape and frontier trends of scientific achievements on EP, provide an overview of the past 120 years and insights for researchers and clinicians to facilitate future collaborative research and clinical intervention. METHODS: Quantitative analysis of publications relating to EP from 1900 to 2020 was interpreted and graphed through the Science Citation Index Expanded of Web of Science Core Collection (limited to SCIE). Microsoft office 2019, GraphPad Prism 8, VOSviewer, and R-bibliometrix were used to conduct the bibliometric analysis. RESULTS: From 1900 to 2020, a total of 1,034 publications were retrieved. The USA had the largest number of publications, making the greatest contribution to the topic (n = 260, 25.15%). Active collaborations between countries/regions were also enrolled. Grant and Hermontaylor were perhaps the most impactful researchers in the landscape of EP. Protein Expression and Purification and the Journal of Biological Chemistry were the most prevalent (79/1,034, 7.64%) and cited journals (n = 2,626), respectively. Using the top 15 citations and co-citations achievements clarified the theoretical basis of the EP research field. Important topics mainly include the structure of EP, the affective factors for activating substrates by EP, EP-related disorders, and inhibitors of EP. CONCLUSION: Based on the bibliometric analysis, we have gained a comprehensive analysis of the global status and research frontiers of studies investigating EP, which provides some guidance and reference for researchers and clinicians engaged in EP research. Frontiers Media S.A. 2022-02-10 /pmc/articles/PMC8866687/ /pubmed/35223895 http://dx.doi.org/10.3389/fmed.2022.779722 Text en Copyright © 2022 Yang, Yin, Peng, Zhang, Li, Cui, Xia, Huang and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Yang, Xiaoli
Yin, Hua
Peng, Lisi
Zhang, Deyu
Li, Keliang
Cui, Fang
Xia, Chuanchao
Huang, Haojie
Li, Zhaoshen
The Global Status and Trends of Enteropeptidase: A Bibliometric Study
title The Global Status and Trends of Enteropeptidase: A Bibliometric Study
title_full The Global Status and Trends of Enteropeptidase: A Bibliometric Study
title_fullStr The Global Status and Trends of Enteropeptidase: A Bibliometric Study
title_full_unstemmed The Global Status and Trends of Enteropeptidase: A Bibliometric Study
title_short The Global Status and Trends of Enteropeptidase: A Bibliometric Study
title_sort global status and trends of enteropeptidase: a bibliometric study
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866687/
https://www.ncbi.nlm.nih.gov/pubmed/35223895
http://dx.doi.org/10.3389/fmed.2022.779722
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