Cargando…

Biodistribution and Dosimetry Evaluation for a Novel Tau Tracer [(18)F]-S16 in Healthy Volunteers and Its Application in Assessment of Tau Pathology in Alzheimer’s Disease

Background: The goal of this study was to report a fully automated radiosynthetic procedure of a novel tau tracer [(18)F]-S16 and its safety, biodistribution, and dosimetry in healthy volunteers as well as the potential utility of [(18)F]-S16 positron emission tomography (PET) in Alzheimer’s disease...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ying, Cai, Li, Zhou, Kaixiang, Cui, Mengchao, Yao, Shaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866701/ https://www.ncbi.nlm.nih.gov/pubmed/35223820 http://dx.doi.org/10.3389/fbioe.2021.812818

Ejemplares similares

(68)Ga-DOTA-DiPSMA PET/CT Imaging: Biodistribution, Dosimetry, and Preliminary Application in Prostate Cancer
por: Zhang, Jiaying, et al.
Publicado: (2022)

In vivo imaging of tau deposition in Alzheimer’s disease using both [(18)F]-THK5317 and [(18)F]-S16: A pilot human study
por: Fu, Liping, et al.
Publicado: (2022)

Radiation dosimetry and pharmacokinetics of the tau PET tracer florzolotau (18F) in healthy Japanese subjects
por: Miyamoto, Masaomi, et al.
Publicado: (2023)

Human biodistribution and radiation dosimetry of the demyelination tracer [(18)F]3F4AP
por: Brugarolas, Pedro, et al.
Publicado: (2022)

Dosimetry and efficacy of a tau PET tracer [(18)F]MK-6240 in Japanese healthy elderly and patients with Alzheimer’s disease
por: Ohnishi, Akihito, et al.
Publicado: (2022)

Biodistribution of a Mitochondrial Metabolic Tracer, [(18)F]F-AraG, in Healthy Volunteers
por: Levi, Jelena, et al.
Publicado: (2022)

Discovery and preclinical characterization of [(18)F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other tauopathies
por: Kroth, Heiko, et al.
Publicado: (2019)

Clinical evaluation of [(18)F] JNJ-64326067, a novel candidate PET tracer for the detection of tau pathology in Alzheimer’s disease
por: Schmidt, Mark E., et al.
Publicado: (2020)

The clinical safety, biodistribution and internal radiation dosimetry of [(18)F]AH113804 in healthy adult volunteers
por: Somer, E. J., et al.
Publicado: (2016)

Safety, Biodistribution, and Radiation Dosimetry of (18)F-rhPSMA-7.3 in Healthy Adult Volunteers
por: Tolvanen, Tuula, et al.
Publicado: (2021)

Comparison of New Tau PET-Tracer Candidates With [(18)F]T808 and [(18)F]T807
por: Declercq, Lieven, et al.
Publicado: (2016)

Clinical translation of (18)F-fluoropivalate – a PET tracer for imaging short-chain fatty acid metabolism: safety, biodistribution, and dosimetry in fed and fasted healthy volunteers
por: Dubash, Suraiya R., et al.
Publicado: (2020)

The clinical safety, biodistribution and internal radiation dosimetry of flutemetamol ((18)F) injection in healthy Japanese adult volunteers
por: Senda, Michio, et al.
Publicado: (2015)

Tauvid™: The First FDA-Approved PET Tracer for Imaging Tau Pathology in Alzheimer’s Disease
por: Jie, Caitlin V. M. L., et al.
Publicado: (2021)

SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy
por: Muñiz, Javier Andrés, et al.
Publicado: (2022)

(18)F‐AV‐1451 and CSF T‐tau and P‐tau as biomarkers in Alzheimer's disease
por: Mattsson, Niklas, et al.
Publicado: (2017)

Head-to-head comparison of tau positron emission tomography tracers [(18)F]flortaucipir and [(18)F]RO948
por: Smith, Ruben, et al.
Publicado: (2019)

Safety and biodistribution of exosomes derived from human induced pluripotent stem cells
por: Gu, Zhewei, et al.
Publicado: (2022)

Comparing (18)F-AV-1451 with CSF t-tau and p-tau for diagnosis of Alzheimer disease
por: Mattsson, Niklas, et al.
Publicado: (2018)

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution
por: Chen, Yen-Hsi, et al.
Publicado: (2023)

Robustifying Experimental Tracer Design for(13)C-Metabolic Flux Analysis
por: Beyß, Martin, et al.
Publicado: (2021)

Nerve regeneration in transplanted organs and tracer imaging studies: A review
por: Huang, Yan, et al.
Publicado: (2022)

Longitudinal in vivo biodistribution of nano and micro sized hydroxyapatite particles implanted in a bone defect
por: Liu, Yang, et al.
Publicado: (2022)

Preclinical biodistribution and dosimetry and human biodistribution comparing (18)F-rhPSMA-7 and single isomer (18)F-rhPSMA-7.3
por: Knorr, Karina, et al.
Publicado: (2022)

Evaluation of the biodistribution and radiation dosimetry of the (18)F-labelled amyloid imaging probe [(18)F]FACT in humans
por: Shidahara, Miho, et al.
Publicado: (2013)

Optimization and Biodistribution of [(11)C]-TKF, An Analog of Tau Protein Imaging Agent [(18)F]-THK523
por: Kong, Yanyan, et al.
Publicado: (2016)

Discriminatory ability of next-generation tau PET tracers for Alzheimer’s disease
por: Yap, Steven Y, et al.
Publicado: (2021)

First-in-human study of a novel cell death tracer [(99m)Tc]Tc-Duramycin: safety, biodistribution and radiation dosimetry in healthy volunteers
por: Metelerkamp Cappenberg, Taco, et al.
Publicado: (2023)

Biodistribution and radiation dosimetry of multiple tracers on total-body positron emission tomography/computed tomography
por: Li, Lianghua, et al.
Publicado: (2023)

Multicenter (18)F-PI-2620 PET for In Vivo Braak Staging of Tau Pathology in Alzheimer’s Disease
por: Rullmann, Michael, et al.
Publicado: (2022)

Biodistribution and radiation dosimetry of the novel hypoxia PET probe [(18)F]DiFA and comparison with [(18)F]FMISO
por: Watanabe, Shiro, et al.
Publicado: (2019)

Safety, biodistribution and radiation dosimetry of [(123)I]ioflupane in healthy Chinese volunteers
por: Zhang, Min, et al.
Publicado: (2023)

Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue
por: Aguero, Cinthya, et al.
Publicado: (2019)

Recent developments on the application of molecular probes in multiple myeloma: Beyond [(18)F]FDG
por: Zhang, Shaojuan, et al.
Publicado: (2022)

The value of (18)F-NaF PET/CT in the diagnosis of bone metastases in patients with nasopharyngeal carcinoma using visual and quantitative analyses
por: Wang, Dong, et al.
Publicado: (2022)

Characterization of the Biodistribution of a Silica Vesicle Nanovaccine Carrying a Rhipicephalus (Boophilus) microplus Protective Antigen With in vivo Live Animal Imaging
por: Mody, Karishma T., et al.
Publicado: (2021)

The Sensitivity of Tau Tracers for the Discrimination of Alzheimer’s Disease Patients and Healthy Controls by PET
por: Mohammadi, Zohreh, et al.
Publicado: (2023)

Assessment of Tau Pathology as Measured by (18)F-THK5317 and (18)F-Flortaucipir PET and Their Relation to Brain Atrophy and Cognition in Alzheimer’s Disease
por: Colato, Elisa, et al.
Publicado: (2021)

(18)F-ASEM Imaging for Evaluating Atherosclerotic Plaques Linked to α7-Nicotinic Acetylcholine Receptor
por: Yang, Tao, et al.
Publicado: (2021)

Evaluation of [(18)F]PI-2620, a second-generation selective tau tracer, for assessing four-repeat tauopathies
por: Tezuka, Toshiki, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qk2c2u57cftr66d2gvgt9sb6cc