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Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems
The modern Gastroenterology have witnessed an essential stride since Helicobacter pylori was first found in the stomach and then its pathogenic effect was discovered. According to the researches conducted during the nearly 40 years, it has been found that this bacterium is associated with a natural...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866759/ https://www.ncbi.nlm.nih.gov/pubmed/35222423 http://dx.doi.org/10.3389/fimmu.2022.833424 |
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author | Wang, Li Cao, Zheng-Min Zhang, Li-Li Dai, Xin-can Liu, Zhen-ju Zeng, Yi-xian Li, Xin-Ye Wu, Qing-Juan Lv, Wen-liang |
author_facet | Wang, Li Cao, Zheng-Min Zhang, Li-Li Dai, Xin-can Liu, Zhen-ju Zeng, Yi-xian Li, Xin-Ye Wu, Qing-Juan Lv, Wen-liang |
author_sort | Wang, Li |
collection | PubMed |
description | The modern Gastroenterology have witnessed an essential stride since Helicobacter pylori was first found in the stomach and then its pathogenic effect was discovered. According to the researches conducted during the nearly 40 years, it has been found that this bacterium is associated with a natural history of many upper gastrointestinal diseases. Epidemiological data show an increased incidence of autoimmune disorders with or after infection with specific microorganisms. The researches have revealed that H. pylori is a potential trigger of gastric autoimmunity, and it may be associated with other autoimmune diseases, both innate and acquired. This paper reviews the current support or opposition about H. pylori as the role of potential triggers of autoimmune diseases, including inflammatory bowel disease, autoimmune thyroiditis, type 1 diabetes mellitus, autoimmune liver diseases, rheumatoid arthritis, idiopathic thrombocytopenic purpura, systemic lupus erythematosus, as well as Sjogren’s syndrome, chronic urticaria and psoriasis, and tried to explain the possible mechanisms. |
format | Online Article Text |
id | pubmed-8866759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88667592022-02-25 Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems Wang, Li Cao, Zheng-Min Zhang, Li-Li Dai, Xin-can Liu, Zhen-ju Zeng, Yi-xian Li, Xin-Ye Wu, Qing-Juan Lv, Wen-liang Front Immunol Immunology The modern Gastroenterology have witnessed an essential stride since Helicobacter pylori was first found in the stomach and then its pathogenic effect was discovered. According to the researches conducted during the nearly 40 years, it has been found that this bacterium is associated with a natural history of many upper gastrointestinal diseases. Epidemiological data show an increased incidence of autoimmune disorders with or after infection with specific microorganisms. The researches have revealed that H. pylori is a potential trigger of gastric autoimmunity, and it may be associated with other autoimmune diseases, both innate and acquired. This paper reviews the current support or opposition about H. pylori as the role of potential triggers of autoimmune diseases, including inflammatory bowel disease, autoimmune thyroiditis, type 1 diabetes mellitus, autoimmune liver diseases, rheumatoid arthritis, idiopathic thrombocytopenic purpura, systemic lupus erythematosus, as well as Sjogren’s syndrome, chronic urticaria and psoriasis, and tried to explain the possible mechanisms. Frontiers Media S.A. 2022-02-10 /pmc/articles/PMC8866759/ /pubmed/35222423 http://dx.doi.org/10.3389/fimmu.2022.833424 Text en Copyright © 2022 Wang, Cao, Zhang, Dai, Liu, Zeng, Li, Wu and Lv https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Wang, Li Cao, Zheng-Min Zhang, Li-Li Dai, Xin-can Liu, Zhen-ju Zeng, Yi-xian Li, Xin-Ye Wu, Qing-Juan Lv, Wen-liang Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems |
title | Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems |
title_full | Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems |
title_fullStr | Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems |
title_full_unstemmed | Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems |
title_short | Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems |
title_sort | helicobacter pylori and autoimmune diseases: involving multiple systems |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866759/ https://www.ncbi.nlm.nih.gov/pubmed/35222423 http://dx.doi.org/10.3389/fimmu.2022.833424 |
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