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Significance of Glycemic Variability in Diabetes Mellitus
The goal of diabetes treatment is to maintain good glycemic control, prevent the development and progression of diabetic complications, and ensure the same quality of life and life expectancy as healthy people. Hemoglobin A1c (HbA1c) is used as an index of glycemic control, but strict glycemic contr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866772/ https://www.ncbi.nlm.nih.gov/pubmed/34544956 http://dx.doi.org/10.2169/internalmedicine.8424-21 |
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author | Kusunoki, Yoshiki Konishi, Kosuke Tsunoda, Taku Koyama, Hidenori |
author_facet | Kusunoki, Yoshiki Konishi, Kosuke Tsunoda, Taku Koyama, Hidenori |
author_sort | Kusunoki, Yoshiki |
collection | PubMed |
description | The goal of diabetes treatment is to maintain good glycemic control, prevent the development and progression of diabetic complications, and ensure the same quality of life and life expectancy as healthy people. Hemoglobin A1c (HbA1c) is used as an index of glycemic control, but strict glycemic control using HbA1c as an index may lead to severe hypoglycemia and cardiovascular death. Glycemic variability (GV), such as excessive hyperglycemia and hypoglycemia, is associated with diabetic vascular complications and has been recognized as an important index of glycemic control. Here, we reviewed the definition and evaluated the clinical usefulness of GV, and its relationship with diabetic complications and therapeutic strategies to reduce GV. |
format | Online Article Text |
id | pubmed-8866772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-88667722022-03-14 Significance of Glycemic Variability in Diabetes Mellitus Kusunoki, Yoshiki Konishi, Kosuke Tsunoda, Taku Koyama, Hidenori Intern Med Review Article The goal of diabetes treatment is to maintain good glycemic control, prevent the development and progression of diabetic complications, and ensure the same quality of life and life expectancy as healthy people. Hemoglobin A1c (HbA1c) is used as an index of glycemic control, but strict glycemic control using HbA1c as an index may lead to severe hypoglycemia and cardiovascular death. Glycemic variability (GV), such as excessive hyperglycemia and hypoglycemia, is associated with diabetic vascular complications and has been recognized as an important index of glycemic control. Here, we reviewed the definition and evaluated the clinical usefulness of GV, and its relationship with diabetic complications and therapeutic strategies to reduce GV. The Japanese Society of Internal Medicine 2021-09-18 2022-02-01 /pmc/articles/PMC8866772/ /pubmed/34544956 http://dx.doi.org/10.2169/internalmedicine.8424-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Kusunoki, Yoshiki Konishi, Kosuke Tsunoda, Taku Koyama, Hidenori Significance of Glycemic Variability in Diabetes Mellitus |
title | Significance of Glycemic Variability in Diabetes Mellitus |
title_full | Significance of Glycemic Variability in Diabetes Mellitus |
title_fullStr | Significance of Glycemic Variability in Diabetes Mellitus |
title_full_unstemmed | Significance of Glycemic Variability in Diabetes Mellitus |
title_short | Significance of Glycemic Variability in Diabetes Mellitus |
title_sort | significance of glycemic variability in diabetes mellitus |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866772/ https://www.ncbi.nlm.nih.gov/pubmed/34544956 http://dx.doi.org/10.2169/internalmedicine.8424-21 |
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