Cargando…

Immunotherapy-responsive Non-paraneoplastic Encephalitis with Antibodies against GAD, LGI1, and GABA(A) Receptor

A 62-year-old man showed abnormal behavior. Brain magnetic resonance imaging revealed multifocal lesions on T2-weighted images. Initial screening revealed that he was seropositive for antibodies against glutamate decarboxylase, which usually indicates treatment resistance to autoimmune encephalitis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakano, Takahiro, Chihara, Norio, Matoba, Kento, Tachibana, Hisatsugu, Okuda, Shiho, Otsuka, Yoshihisa, Ueda, Takehiro, Sekiguchi, Kenji, Kowa, Hisatomo, Leypoldt, Frank, Wandinger, Klaus-Peter, Matsumoto, Riki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Internal Medicine 2021
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866773/ https://www.ncbi.nlm.nih.gov/pubmed/34334569 http://dx.doi.org/10.2169/internalmedicine.7846-21

Ejemplares similares

Long-Surviving Adult Siblings With Joubert Syndrome Harboring a Novel Compound Heterozygous CPLANE1 Variant
por: Matoba, Kento, et al.
Publicado: (2022)

Japanese WDR45 de novo mutation diagnosed by exome analysis: A case report
por: Endo, Hironobu, et al.
Publicado: (2017)

Circulating plasmablasts and follicular helper T-cell subsets are associated with antibody-positive autoimmune epilepsy
por: Hara, Atsushi, et al.
Publicado: (2022)

Paraneoplastic NMOSD associated with EG junction adenocarcinoma expressing unprotected AQP4
por: Sudo, Atsushi, et al.
Publicado: (2018)

Regional glucose hypometabolic spread within the primary motor cortex is associated with amyotrophic lateral sclerosis disease progression: A fluoro-deoxyglucose positron emission tomography study
por: Endo, Hironobu, et al.
Publicado: (2017)

Spontaneous Downbeat Nystagmus in Anti-GAD-Antibody-Associated Paraneoplastic Syndrome
por: Shivaram, Sumanth, et al.
Publicado: (2022)

GABA(A) receptor and LGI1 antibody encephalitis in a patient with thymoma
por: Simabukuro, Mateus Mistieri, et al.
Publicado: (2015)

Immunoreactivity for GABA, GAD65, GAD67 and Bestrophin-1 in the Meninges and the Choroid Plexus: Implications for Non-Neuronal Sources for GABA in the Developing Mouse Brain
por: Tochitani, Shiro, et al.
Publicado: (2013)

Antibody Properties Associate with Clinical Phenotype in LGI1 Encephalitis
por: Ludewig, Susann, et al.
Publicado: (2023)

Paraneoplastic anti-GAD65 extralimbic encephalitis presented with epilepsy: A case report
por: Xia, Si-Qi, et al.
Publicado: (2023)

Autoimmune encephalitis with coexistent LGI1 and GABA(B)R1 antibodies: case report
por: Xie, Yi, et al.
Publicado: (2021)

Two Cases of Acute Disseminated Encephalomyelitis Following Vaccination Against Human Papilloma Virus
por: Sekiguchi, Kenji, et al.
Publicado: (2016)

CSF Findings in Acute NMDAR and LGI1 Antibody–Associated Autoimmune Encephalitis
por: Dürr, Marc, et al.
Publicado: (2021)

Evaluation of seizure treatment in anti-LGI1, anti-NMDAR, and anti-GABA(B)R encephalitis
por: de Bruijn, Marienke A.A.M., et al.
Publicado: (2019)

Seizures and risk of epilepsy in anti‐NMDAR, anti‐LGI1, and anti‐GABA(B)R encephalitis
por: Shen, Chun‐Hong, et al.
Publicado: (2020)

Cognitive Impairment and the correlation with genetic Expression of GAD67, Gad65 and GABA beta2 Using Human Induced Pluripotent Stem Cells
por: Khalifa, D., et al.
Publicado: (2022)

Compartmentalization of GABA Synthesis by GAD67 Differs between Pancreatic Beta Cells and Neurons
por: Kanaani, Jamil, et al.
Publicado: (2015)

Common Distribution of gad Operon in Lactobacillus brevis and its GadA Contributes to Efficient GABA Synthesis toward Cytosolic Near-Neutral pH
por: Wu, Qinglong, et al.
Publicado: (2017)

LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
por: Sagane, Koji, et al.
Publicado: (2008)

The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats
por: Naseri, Masoud, et al.
Publicado: (2017)

Combinational Spinal GAD65 Gene Delivery and Systemic GABA-Mimetic Treatment for Modulation of Spasticity
por: Kakinohana, Osamu, et al.
Publicado: (2012)

TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila CNS
por: Romano, Giulia, et al.
Publicado: (2021)

Paraneoplastic Neuromyelitis Optica Spectrum Disorder Associated with Atypical Thymic Carcinoid: A Case Report
por: Mitsui, Suguru, et al.
Publicado: (2021)

LGI proteins in the nervous system
por: Kegel, Linde, et al.
Publicado: (2013)

Good MRI images: to Gad or not to Gad?
por: Steen, Henning, et al.
Publicado: (2007)

Paraneoplastic encephalomyeloradiculits with multiple autoantibodies against ITPR-1, GFAP and MOG: case report and literature review
por: Cirkel, Anna, et al.
Publicado: (2021)

LGI1 expression and human brain asymmetry: insights from patients with LGI1-antibody encephalitis
por: Jang, Yoonhyuk, et al.
Publicado: (2018)

Positive LGI1 Antibodies in CSF and Relapse Relate to Worse Outcome in Anti-LGI1 Encephalitis
por: Cui, Li-li, et al.
Publicado: (2021)

Investigating the Role of GABA in Neural Development and Disease Using Mice Lacking GAD67 or VGAT Genes
por: Bolneo, Erika, et al.
Publicado: (2022)

LGI Proteins and Epilepsy in Human and Animals
por: Pakozdy, A., et al.
Publicado: (2015)

Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2
por: Limviphuvadh, Vachiranee, et al.
Publicado: (2010)

Transcription Factor c-Maf Promotes Immunoregulation of Programmed Cell Death 1–Expressed CD8(+) T Cells in Multiple Sclerosis
por: Koto, Shusuke, et al.
Publicado: (2022)

GABA and Combined GABA with GAD65-Alum Treatment Alters Th1 Cytokine Responses of PBMCs from Children with Recent-Onset Type 1 Diabetes
por: Heath, Katie E., et al.
Publicado: (2023)

Action-rule-based cognitive control enables efficient execution of stimulus–response conflict tasks: a model validation of Simon task performance
por: Otani, Yoshitaka, et al.
Publicado: (2023)

Guilty by Association: KCTD16 and GABA(B)R Antibodies in Paraneoplastic Limbic Encephalitis
por: Gaspard, Nicolas
Publicado: (2019)

Tonic activation of GABA(B) receptors via GAT-3 mediated GABA release reduces network activity in the developing somatosensory cortex in GAD67-GFP mice
por: Ueberbach, Timo, et al.
Publicado: (2023)

Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy
por: Jarius, Sven, et al.
Publicado: (2016)

Isolated Chorea Associated with LGI1 Antibody
por: Ramdhani, Ritesh A., et al.
Publicado: (2014)

Striatum Involvement in LGI1 Limbic Encephalitis
por: Plantone, Domenico
Publicado: (2018)

Psychiatric Manifestation of Anti-LGI1 Encephalitis
por: Endres, Dominique, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2424rgmlkp0febmn9hhfs1fal2