Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review

A 60-year-old Japanese woman was diagnosed with celiac disease (CeD) and treated with a gluten-free diet. For five years, she had a good clinical course. However, she complained of inappetence and nausea. Colonoscopy revealed ulcerative tumors in the terminal ileum. A histological examination of bio...

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Autores principales: Ishibashi, Hideki, Imakiire, So, Goto, Maki, Nomaru, Ryohei, Shibata, Mamoru, Matsuoka, Hiroki, Yasuda, Hideki, Yamashima, Tomomi, Sakisaka, Hideto, Tanabe, Taro, Matsuoka, Satoshi, Kuno, Nobuaki, Abe, Koichi, Funakoshi, Sadahiro, Takamatsu, Yasushi, Hirai, Fumihito, Takeshita, Morishige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866777/
https://www.ncbi.nlm.nih.gov/pubmed/34334570
http://dx.doi.org/10.2169/internalmedicine.7876-21
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author Ishibashi, Hideki
Imakiire, So
Goto, Maki
Nomaru, Ryohei
Shibata, Mamoru
Matsuoka, Hiroki
Yasuda, Hideki
Yamashima, Tomomi
Sakisaka, Hideto
Tanabe, Taro
Matsuoka, Satoshi
Kuno, Nobuaki
Abe, Koichi
Funakoshi, Sadahiro
Takamatsu, Yasushi
Hirai, Fumihito
Takeshita, Morishige
author_facet Ishibashi, Hideki
Imakiire, So
Goto, Maki
Nomaru, Ryohei
Shibata, Mamoru
Matsuoka, Hiroki
Yasuda, Hideki
Yamashima, Tomomi
Sakisaka, Hideto
Tanabe, Taro
Matsuoka, Satoshi
Kuno, Nobuaki
Abe, Koichi
Funakoshi, Sadahiro
Takamatsu, Yasushi
Hirai, Fumihito
Takeshita, Morishige
author_sort Ishibashi, Hideki
collection PubMed
description A 60-year-old Japanese woman was diagnosed with celiac disease (CeD) and treated with a gluten-free diet. For five years, she had a good clinical course. However, she complained of inappetence and nausea. Colonoscopy revealed ulcerative tumors in the terminal ileum. A histological examination of biopsy specimens from the ulcerative tumor showed diffuse infiltration of large atypical lymphocytes. Immunohistologically, the atypical lymphoid cells were positive for cluster of differentiation (CD)10 and CD20. Many Epstein-Barr virus-encoded small RNA (EBER)-positive atypical lymphocytes were detected by in situ hybridization. This represents the first reported case of Epstein-Barr virus-positive intestinal diffuse large B-cell lymphoma complicated with CeD.
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spelling pubmed-88667772022-03-14 Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review Ishibashi, Hideki Imakiire, So Goto, Maki Nomaru, Ryohei Shibata, Mamoru Matsuoka, Hiroki Yasuda, Hideki Yamashima, Tomomi Sakisaka, Hideto Tanabe, Taro Matsuoka, Satoshi Kuno, Nobuaki Abe, Koichi Funakoshi, Sadahiro Takamatsu, Yasushi Hirai, Fumihito Takeshita, Morishige Intern Med Case Report A 60-year-old Japanese woman was diagnosed with celiac disease (CeD) and treated with a gluten-free diet. For five years, she had a good clinical course. However, she complained of inappetence and nausea. Colonoscopy revealed ulcerative tumors in the terminal ileum. A histological examination of biopsy specimens from the ulcerative tumor showed diffuse infiltration of large atypical lymphocytes. Immunohistologically, the atypical lymphoid cells were positive for cluster of differentiation (CD)10 and CD20. Many Epstein-Barr virus-encoded small RNA (EBER)-positive atypical lymphocytes were detected by in situ hybridization. This represents the first reported case of Epstein-Barr virus-positive intestinal diffuse large B-cell lymphoma complicated with CeD. The Japanese Society of Internal Medicine 2021-07-30 2022-02-01 /pmc/articles/PMC8866777/ /pubmed/34334570 http://dx.doi.org/10.2169/internalmedicine.7876-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ishibashi, Hideki
Imakiire, So
Goto, Maki
Nomaru, Ryohei
Shibata, Mamoru
Matsuoka, Hiroki
Yasuda, Hideki
Yamashima, Tomomi
Sakisaka, Hideto
Tanabe, Taro
Matsuoka, Satoshi
Kuno, Nobuaki
Abe, Koichi
Funakoshi, Sadahiro
Takamatsu, Yasushi
Hirai, Fumihito
Takeshita, Morishige
Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review
title Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review
title_full Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review
title_fullStr Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review
title_full_unstemmed Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review
title_short Epstein-Barr Virus-positive Intestinal Diffuse Large B-cell Lymphoma in a Japanese Patient with Celiac Disease: First Reported Case and a Literature Review
title_sort epstein-barr virus-positive intestinal diffuse large b-cell lymphoma in a japanese patient with celiac disease: first reported case and a literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866777/
https://www.ncbi.nlm.nih.gov/pubmed/34334570
http://dx.doi.org/10.2169/internalmedicine.7876-21
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