Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis

Immunoglobulin-G4-related disease (IgG4-RD) is a multi-organ systemic inflammatory disorder. The ideal treatment of coronary artery involvement in IgG4-RD remains uncertain due to its rarity. We herein report a case of coronary artery involvement with IgG4-RD, wherein mass lesions surrounded the cor...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubota, Naoki, Ozaki, Kazuyuki, Hoyano, Makoto, Okubo, Takeshi, Kimura, Shinpei, Yanagawa, Takao, Kashimura, Takeshi, Inomata, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866778/
https://www.ncbi.nlm.nih.gov/pubmed/35110514
http://dx.doi.org/10.2169/internalmedicine.7880-21
_version_ 1784655907596009472
author Kubota, Naoki
Ozaki, Kazuyuki
Hoyano, Makoto
Okubo, Takeshi
Kimura, Shinpei
Yanagawa, Takao
Kashimura, Takeshi
Inomata, Takayuki
author_facet Kubota, Naoki
Ozaki, Kazuyuki
Hoyano, Makoto
Okubo, Takeshi
Kimura, Shinpei
Yanagawa, Takao
Kashimura, Takeshi
Inomata, Takayuki
author_sort Kubota, Naoki
collection PubMed
description Immunoglobulin-G4-related disease (IgG4-RD) is a multi-organ systemic inflammatory disorder. The ideal treatment of coronary artery involvement in IgG4-RD remains uncertain due to its rarity. We herein report a case of coronary artery involvement with IgG4-RD, wherein mass lesions surrounded the coronary arteries with a moderate stenosis lesion in the right coronary artery (RCA). The fractional flow reserve (FFR) of the RCA was 0.76. After steroid therapy, the mass lesions around the coronary arteries improved. The FFR of the RCA also improved from 0.76 to 0.86. These findings suggest the efficacy of using steroid therapy for coronary artery involvement with IgG4-RD.
format Online
Article
Text
id pubmed-8866778
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-88667782022-03-14 Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis Kubota, Naoki Ozaki, Kazuyuki Hoyano, Makoto Okubo, Takeshi Kimura, Shinpei Yanagawa, Takao Kashimura, Takeshi Inomata, Takayuki Intern Med Case Report Immunoglobulin-G4-related disease (IgG4-RD) is a multi-organ systemic inflammatory disorder. The ideal treatment of coronary artery involvement in IgG4-RD remains uncertain due to its rarity. We herein report a case of coronary artery involvement with IgG4-RD, wherein mass lesions surrounded the coronary arteries with a moderate stenosis lesion in the right coronary artery (RCA). The fractional flow reserve (FFR) of the RCA was 0.76. After steroid therapy, the mass lesions around the coronary arteries improved. The FFR of the RCA also improved from 0.76 to 0.86. These findings suggest the efficacy of using steroid therapy for coronary artery involvement with IgG4-RD. The Japanese Society of Internal Medicine 2022-02-01 2022-02-01 /pmc/articles/PMC8866778/ /pubmed/35110514 http://dx.doi.org/10.2169/internalmedicine.7880-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kubota, Naoki
Ozaki, Kazuyuki
Hoyano, Makoto
Okubo, Takeshi
Kimura, Shinpei
Yanagawa, Takao
Kashimura, Takeshi
Inomata, Takayuki
Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis
title Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis
title_full Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis
title_fullStr Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis
title_full_unstemmed Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis
title_short Improvement of Mass Lesions around Coronary Arteries and Fractional Flow Reserve after Steroid Therapy in Immunoglobulin-G4-related Coronary Periarteritis
title_sort improvement of mass lesions around coronary arteries and fractional flow reserve after steroid therapy in immunoglobulin-g4-related coronary periarteritis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866778/
https://www.ncbi.nlm.nih.gov/pubmed/35110514
http://dx.doi.org/10.2169/internalmedicine.7880-21
work_keys_str_mv AT kubotanaoki improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis
AT ozakikazuyuki improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis
AT hoyanomakoto improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis
AT okubotakeshi improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis
AT kimurashinpei improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis
AT yanagawatakao improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis
AT kashimuratakeshi improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis
AT inomatatakayuki improvementofmasslesionsaroundcoronaryarteriesandfractionalflowreserveaftersteroidtherapyinimmunoglobuling4relatedcoronaryperiarteritis

Ejemplares similares