Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus

A 21-year-old Japanese man without known diabetes mellitus had abdominal pain. The diagnosis was ketoacidosis and hypertriglyceridemia-induced acute pancreatitis. He had polydipsia and polyuria and had habitually drunk several soft drinks every day for two years. After hospitalization, despite adequ...

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Autores principales: Tsujimoto, Yasutaka, Nakamura, Tomoaki, Onishi, Jun, Ishimaru, Naoto, Iwata, Naoko, Fujisawa, Haruki, Suzuki, Atsushi, Sugimura, Yoshihisa, Chihara, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866797/
https://www.ncbi.nlm.nih.gov/pubmed/34373377
http://dx.doi.org/10.2169/internalmedicine.7663-21
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author Tsujimoto, Yasutaka
Nakamura, Tomoaki
Onishi, Jun
Ishimaru, Naoto
Iwata, Naoko
Fujisawa, Haruki
Suzuki, Atsushi
Sugimura, Yoshihisa
Chihara, Kazuo
author_facet Tsujimoto, Yasutaka
Nakamura, Tomoaki
Onishi, Jun
Ishimaru, Naoto
Iwata, Naoko
Fujisawa, Haruki
Suzuki, Atsushi
Sugimura, Yoshihisa
Chihara, Kazuo
author_sort Tsujimoto, Yasutaka
collection PubMed
description A 21-year-old Japanese man without known diabetes mellitus had abdominal pain. The diagnosis was ketoacidosis and hypertriglyceridemia-induced acute pancreatitis. He had polydipsia and polyuria and had habitually drunk several soft drinks every day for two years. After hospitalization, despite adequate liquid intake, dehydration remained with hypotonic polyuria. Further examinations revealed the coexistence of central diabetes insipidus (CDI), possibly caused by lymphocytic infundibulo-neurohypophysitis, based on anti-rabphilin-3A antibody positivity. Although CDI had been undiagnosed for two years, over-consumption of sugar-rich soft drinks to ease thirst caused ketoacidosis, hypertriglyceridemia, and acute pancreatitis. There are no previous reports of this three-part combination of symptoms caused by CDI.
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spelling pubmed-88667972022-03-14 Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus Tsujimoto, Yasutaka Nakamura, Tomoaki Onishi, Jun Ishimaru, Naoto Iwata, Naoko Fujisawa, Haruki Suzuki, Atsushi Sugimura, Yoshihisa Chihara, Kazuo Intern Med Case Report A 21-year-old Japanese man without known diabetes mellitus had abdominal pain. The diagnosis was ketoacidosis and hypertriglyceridemia-induced acute pancreatitis. He had polydipsia and polyuria and had habitually drunk several soft drinks every day for two years. After hospitalization, despite adequate liquid intake, dehydration remained with hypotonic polyuria. Further examinations revealed the coexistence of central diabetes insipidus (CDI), possibly caused by lymphocytic infundibulo-neurohypophysitis, based on anti-rabphilin-3A antibody positivity. Although CDI had been undiagnosed for two years, over-consumption of sugar-rich soft drinks to ease thirst caused ketoacidosis, hypertriglyceridemia, and acute pancreatitis. There are no previous reports of this three-part combination of symptoms caused by CDI. The Japanese Society of Internal Medicine 2021-08-06 2022-02-01 /pmc/articles/PMC8866797/ /pubmed/34373377 http://dx.doi.org/10.2169/internalmedicine.7663-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Tsujimoto, Yasutaka
Nakamura, Tomoaki
Onishi, Jun
Ishimaru, Naoto
Iwata, Naoko
Fujisawa, Haruki
Suzuki, Atsushi
Sugimura, Yoshihisa
Chihara, Kazuo
Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
title Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
title_full Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
title_fullStr Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
title_full_unstemmed Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
title_short Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
title_sort ketoacidosis, hypertriglyceridemia and acute pancreatitis induced by soft drink polydipsia in a patient with occult central diabetes insipidus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866797/
https://www.ncbi.nlm.nih.gov/pubmed/34373377
http://dx.doi.org/10.2169/internalmedicine.7663-21
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