Cargando…
Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics
Metronidazole (MTZ) is a clinically important antimicrobial agent that is active against both bacterial and protozoan organisms. MTZ has been used extensively for more than 60 years and until now resistance has been rare. However, a recent and dramatic increase in the number of MTZ resistant bacteri...
Autores principales: | Krakovka, Sascha, Ribacke, Ulf, Miyamoto, Yukiko, Eckmann, Lars, Svärd, Staffan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866875/ https://www.ncbi.nlm.nih.gov/pubmed/35222342 http://dx.doi.org/10.3389/fmicb.2022.834008 |
Ejemplares similares
-
Coordinated Changes in Gene Expression Throughout Encystation of Giardia intestinalis
por: Einarsson, Elin, et al.
Publicado: (2016) -
A Detailed Gene Expression Map of Giardia Encystation
por: Rojas-López, Laura, et al.
Publicado: (2021) -
Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines
por: Ansell, Brendan R. E., et al.
Publicado: (2017) -
Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
por: Majumdar, Soneya, et al.
Publicado: (2023) -
Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery
por: Krakovka, Sascha, et al.
Publicado: (2022)