A new approach in acute myeloid leukemia (AML): Samatya-predicting score

We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determ...

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Detalles Bibliográficos
Autores principales: Serin, Istemi, Orhan, Bagnu, Sonmez, Derya, Cinli, Tahir Alper, Goze, Hasan, Serin, Huriye, Gulesir, Begum, Yokus, Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866886/
https://www.ncbi.nlm.nih.gov/pubmed/35242525
http://dx.doi.org/10.1016/j.lrr.2022.100293
Descripción
Sumario:We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determined as 2,5. The sensitivity for mortality was 88% and the specificity was 42%. In terms of being non-responder to induction therapy, the sensitivity was 90,1%, the specificity was 25,3%. OS was shorter in those with high risk scores. This study makes an important contribution to the literature in terms of creating a different perspective to predict prognosis in AML.

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