A new approach in acute myeloid leukemia (AML): Samatya-predicting score

We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determ...

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Autores principales: Serin, Istemi, Orhan, Bagnu, Sonmez, Derya, Cinli, Tahir Alper, Goze, Hasan, Serin, Huriye, Gulesir, Begum, Yokus, Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866886/
https://www.ncbi.nlm.nih.gov/pubmed/35242525
http://dx.doi.org/10.1016/j.lrr.2022.100293
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author Serin, Istemi
Orhan, Bagnu
Sonmez, Derya
Cinli, Tahir Alper
Goze, Hasan
Serin, Huriye
Gulesir, Begum
Yokus, Osman
author_facet Serin, Istemi
Orhan, Bagnu
Sonmez, Derya
Cinli, Tahir Alper
Goze, Hasan
Serin, Huriye
Gulesir, Begum
Yokus, Osman
author_sort Serin, Istemi
collection PubMed
description We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determined as 2,5. The sensitivity for mortality was 88% and the specificity was 42%. In terms of being non-responder to induction therapy, the sensitivity was 90,1%, the specificity was 25,3%. OS was shorter in those with high risk scores. This study makes an important contribution to the literature in terms of creating a different perspective to predict prognosis in AML.
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spelling pubmed-88668862022-03-02 A new approach in acute myeloid leukemia (AML): Samatya-predicting score Serin, Istemi Orhan, Bagnu Sonmez, Derya Cinli, Tahir Alper Goze, Hasan Serin, Huriye Gulesir, Begum Yokus, Osman Leuk Res Rep Article We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determined as 2,5. The sensitivity for mortality was 88% and the specificity was 42%. In terms of being non-responder to induction therapy, the sensitivity was 90,1%, the specificity was 25,3%. OS was shorter in those with high risk scores. This study makes an important contribution to the literature in terms of creating a different perspective to predict prognosis in AML. Elsevier 2022-02-15 /pmc/articles/PMC8866886/ /pubmed/35242525 http://dx.doi.org/10.1016/j.lrr.2022.100293 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Serin, Istemi
Orhan, Bagnu
Sonmez, Derya
Cinli, Tahir Alper
Goze, Hasan
Serin, Huriye
Gulesir, Begum
Yokus, Osman
A new approach in acute myeloid leukemia (AML): Samatya-predicting score
title A new approach in acute myeloid leukemia (AML): Samatya-predicting score
title_full A new approach in acute myeloid leukemia (AML): Samatya-predicting score
title_fullStr A new approach in acute myeloid leukemia (AML): Samatya-predicting score
title_full_unstemmed A new approach in acute myeloid leukemia (AML): Samatya-predicting score
title_short A new approach in acute myeloid leukemia (AML): Samatya-predicting score
title_sort new approach in acute myeloid leukemia (aml): samatya-predicting score
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866886/
https://www.ncbi.nlm.nih.gov/pubmed/35242525
http://dx.doi.org/10.1016/j.lrr.2022.100293
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