Cell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study

Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae to PB was induced by passagi...

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Detalles Bibliográficos
Autores principales: Chen, Xinyi, Tian, Jingjing, Luo, Can, Wang, Xiaofan, Li, Xianping, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866958/
https://www.ncbi.nlm.nih.gov/pubmed/35222333
http://dx.doi.org/10.3389/fmicb.2022.810403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866958/
https://www.ncbi.nlm.nih.gov/pubmed/35222333
http://dx.doi.org/10.3389/fmicb.2022.810403

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