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In-Vivo Induced CAR-T Cell for the Potential Breakthrough to Overcome the Barriers of Current CAR-T Cell Therapy

Chimeric antigen receptor T cell (CAR-T cell) therapy has shown impressive success in the treatment of hematological malignancies, but the systemic toxicity and complex manufacturing process of current autologous CAR-T cell therapy hinder its broader applications. Universal CAR-T cells have been dev...

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Detalles Bibliográficos
Autores principales: Xin, Tianqing, Cheng, Li, Zhou, Chuchao, Zhao, Yimeng, Hu, Zhenhua, Wu, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866962/
https://www.ncbi.nlm.nih.gov/pubmed/35223491
http://dx.doi.org/10.3389/fonc.2022.809754