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Molecular Changes in the Cardiac RyR2 With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
The cardiac ryanodine receptor Ca(2+) release channel (RyR2) is inserted into the membrane of intracellular sarcoplasmic reticulum (SR) myocyte Ca(2+) stores, where it releases the Ca(2+) essential for contraction. Mutations in proteins involved in Ca(2+) signaling can lead to catecholaminergic poly...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867003/ https://www.ncbi.nlm.nih.gov/pubmed/35222090 http://dx.doi.org/10.3389/fphys.2022.830367 |