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The Effects and Underlying Mechanisms of Hepatitis B Virus X Gene Mutants on the Development of Hepatocellular Carcinoma

We aimed to elucidate the mechanism by which hepatitis B virus X (HBx) mutations increase the occurrence of hepatocellular carcinoma (HCC) and identify novel putative therapeutic targets. Wild-type HBx (WT-HBx) and four HBx mutants (M1, A1762T/G1764A; M2, T1674G+T1753C+A1762T/G1764A; M3, C1653T+T167...

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Detalles Bibliográficos
Autores principales:	Pu, Rui, Liu, Wenbin, Zhou, Xinyu, Chen, Xi, Hou, Xiaomei, Cai, Shiliang, Chen, Liping, Wu, Jianfeng, Yang, Fan, Tan, Xiaojie, Yin, Jianhua, Wang, Xin, Cao, Guangwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867042/ https://www.ncbi.nlm.nih.gov/pubmed/35223517 http://dx.doi.org/10.3389/fonc.2022.836517

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