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Oral treatment of 4-methylumbelliferone reduced perineuronal nets and improved recognition memory in mice

Hyaluronan (HA) is a core constituent of perineuronal nets (PNNs) that surround subpopulations of neurones. The PNNs control synaptic stabilization in both the developing and adult central nervous system, and disruption of PNNs has shown to reactivate neuroplasticity. We investigated the possibility...

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Detalles Bibliográficos
Autores principales:	Dubisova, Jana, Burianova, Jana Svobodova, Svobodova, Lucie, Makovicky, Pavol, Martinez-Varea, Noelia, Cimpean, Anda, Fawcett, James W., Kwok, Jessica C.F., Kubinova, Sarka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867078/ https://www.ncbi.nlm.nih.gov/pubmed/35066096 http://dx.doi.org/10.1016/j.brainresbull.2022.01.011

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