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Exploring the Metabolic Landscape of AML: From Haematopoietic Stem Cells to Myeloblasts and Leukaemic Stem Cells

Despite intensive chemotherapy regimens, up to 60% of adults with acute myeloid leukaemia (AML) will relapse and eventually succumb to their disease. Recent studies suggest that leukaemic stem cells (LSCs) drive AML relapse by residing in the bone marrow niche and adapting their metabolic profile. M...

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Detalles Bibliográficos
Autores principales: Mesbahi, Yashar, Trahair, Toby N., Lock, Richard B., Connerty, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867093/
https://www.ncbi.nlm.nih.gov/pubmed/35223487
http://dx.doi.org/10.3389/fonc.2022.807266

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