The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity

Varicella-zoster virus (VZV) is a human pathogen from the α-subfamily of herpesviruses. The VZV Orf24-Orf27 complex represents the essential viral core nuclear egress complex (NEC) that orchestrates the egress of the preassembled virus capsids from the nucleus. While previous studies have primarily...

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Detalles Bibliográficos
Autores principales: Schweininger, Johannes, Kriegel, Mark, Häge, Sigrun, Conrad, Marcus, Alkhashrom, Sewar, Lösing, Josephine, Weiler, Sigrid, Tillmanns, Julia, Egerer-Sieber, Claudia, Decker, Andrea, Lenac Roviš, Tihana, Eichler, Jutta, Sticht, Heinrich, Marschall, Manfred, Muller, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867122/
https://www.ncbi.nlm.nih.gov/pubmed/35074430
http://dx.doi.org/10.1016/j.jbc.2022.101625

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