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Structural determinants of the dominant conformational epitopes of phospholipase A2 receptor in primary membranous nephropathy

Anti-phospholipase A2 receptor autoantibody (PLA2R-Ab) plays a critical role in the pathogenesis of primary membranous nephropathy (PMN), an autoimmune kidney disease characterized by immune deposits in the glomerular subepithelial spaces and proteinuria. However, the mechanism of how PLA2R-Abs inte...

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Detalles Bibliográficos
Autores principales:	Tang, Hong, Zhu, Richard, Waldman, Meryl, Zhu, Quansheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867125/ https://www.ncbi.nlm.nih.gov/pubmed/35065076 http://dx.doi.org/10.1016/j.jbc.2022.101605

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