Cargando…

Analysis of the Molecular Mechanism of Punicalagin in the Treatment of Alzheimer’s Disease by Computer-Aided Drug Research Technology

[Image: see text] The objective of this work is to explore the effect and potential mechanism of Punicalagin (Pun) in managing Alzheimer’s disease (AD) based on computer-aided drug technology. The following methods were used: the intersection genes of Pun and AD were retrieved from the database and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Ping, Xu, Liang, Huang, Shuyun, Li, Danfeng, Liu, Yanping, Guo, Hongmin, Dai, Niuniu, Hong, Zongyuan, Zhong, Shuzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867547/ https://www.ncbi.nlm.nih.gov/pubmed/35224375 http://dx.doi.org/10.1021/acsomega.1c06565

Ejemplares similares

Network Pharmacology and Intestinal Microbiota Analysis Revealing the Mechanism of Punicalagin Improving Bacterial Enteritis
por: Huang, Shuyun, et al.
Publicado: (2023)

Physiological and Immune Functions of Punicalagin
por: Venusova, Eva, et al.
Publicado: (2021)

Punicalagin Targets Atherosclerosis: Gene Expression Profiling of THP-1 Macrophages Treated with Punicalagin and Molecular Docking
por: Huwait, Etimad, et al.
Publicado: (2022)

Antibiofilm effects of punicalagin against Staphylococcus aureus in vitro
por: Xu, Yunfeng, et al.
Publicado: (2023)

Intestinal microbiota analysis and network pharmacology reveal the mechanism by which Lianhua Qingwen capsule improves the immune function of mice infected with influenza A virus
por: Xu, Ping, et al.
Publicado: (2022)

Punicalagin Regulates Signaling Pathways in Inflammation-Associated Chronic Diseases
por: Xu, Jie, et al.
Publicado: (2021)

Computer Aided Drug Design Methodologies with Natural Products in the Drug Research Against Alzheimer’s Disease
por: de Sousa, Natália Ferreira, et al.
Publicado: (2022)

Research on Computer-Aided Product Design Technology
por: Song, Wei
Publicado: (2022)

Punicalagin in Cancer Prevention—Via Signaling Pathways Targeting
por: Berdowska, Izabela, et al.
Publicado: (2021)

A Comparative Analysis of Punicalagin Interaction with PDIA1 and PDIA3 by Biochemical and Computational Approaches
por: Paglia, Giuliano, et al.
Publicado: (2021)

Punicalagin Induces Serum Low-Density Lipoprotein Influx to Macrophages
por: Atrahimovich, Dana, et al.
Publicado: (2016)

Antifungal potential of punicalagin against Cryptococcus neoformans species complex
por: Silva, Thaísa Cristina, et al.
Publicado: (2018)

Punicalagin Ameliorates Lupus Nephritis via Inhibition of PAR2
por: Seo, Yohan, et al.
Publicado: (2020)

Impact of Punicalagin on the Physicochemical and Structural Properties of Wheat Flour Dough
por: Peng, Hong, et al.
Publicado: (2019)

Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy
por: Luo, Jingfang, et al.
Publicado: (2019)

Potential role of punicalagin against oxidative stress induced testicular damage
por: Rao, Faiza, et al.
Publicado: (2016)

Transcriptomic analysis of Bursaphelenchus xylophilus treated by a potential phytonematicide, punicalagin
por: Guo, Qun-Qun, et al.
Publicado: (2020)

Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia
por: Subkorn, Paweena, et al.
Publicado: (2021)

The Role of Punicalagin and Its Metabolites in Atherosclerosis and Risk Factors Associated with the Disease
por: Alalawi, Sulaiman, et al.
Publicado: (2023)

Protective Effects of Punicalagin on Osteoporosis by Inhibiting Osteoclastogenesis and Inflammation via the NF-κB and MAPK Pathways
por: Wang, Wei, et al.
Publicado: (2020)

Antifungal activity of pomegranate peel extract and isolated compound punicalagin against dermatophytes
por: Foss, Simone R, et al.
Publicado: (2014)

Punicalagin Mollifies Lead Acetate-Induced Oxidative Imbalance in Male Reproductive System
por: Rao, Faiza, et al.
Publicado: (2016)

Punicalagin Regulates Key Processes Associated with Atherosclerosis in THP-1 Cellular Model
por: Almowallad, Sanaa, et al.
Publicado: (2020)

Lung-protective effect of Punicalagin on LPS-induced acute lung injury in mice
por: Zeng, Yibin, et al.
Publicado: (2022)

Punicalagin-Loaded Alginate/Chitosan-Gallol Hydrogels for Efficient Wound Repair and Hemostasis
por: Ju, Jaewon, et al.
Publicado: (2022)

Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation
por: Cao, Ke, et al.
Publicado: (2015)

Potential therapeutic role of punicalagin against mechanical-trauma-induced stress urinary incontinence via upregulation of Nrf2 and TGF-β1 signaling: Effect of punicalagin on mechanical trauma induced SUI
por: Tang, Jianming, et al.
Publicado: (2017)

Computer-Aided Applications in Pharmaceutical Technology
por: Djuris, J
Publicado: (2013)

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
por: An, Xin, et al.
Publicado: (2020)

Inhibitory Effect of Punicalagin on Inflammatory and Angiogenic Activation of Human Umbilical Vein Endothelial Cells
por: Liu, Wei, et al.
Publicado: (2021)

A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy
por: Cao, Yuan, et al.
Publicado: (2021)

Punicalagin Protects against Diabetic Liver Injury by Upregulating Mitophagy and Antioxidant Enzyme Activities
por: Zhang, Yahui, et al.
Publicado: (2022)

Computer-Aided Drug Design Applied to Marine Drug Discovery: Meridianins as Alzheimer’s Disease Therapeutic Agents
por: Llorach-Pares, Laura, et al.
Publicado: (2017)

Computer-aided drug discovery
por: Bajorath, Jürgen
Publicado: (2015)

Computer-aided drug design
por: Ece, Abdulilah
Publicado: (2023)

Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry
por: Lin, Liang-Tzung, et al.
Publicado: (2013)

Punicalagin inhibited proliferation, invasion and angiogenesis of osteosarcoma through suppression of NF-κB signaling
por: Huang, Tao, et al.
Publicado: (2020)

Punicalagin Regulates Apoptosis-Autophagy Switch via Modulation of Annexin A1 in Colorectal Cancer
por: Ganesan, Thanusha, et al.
Publicado: (2020)

Effect of punicalagin and human chorionic gonadotropin on body weight and reproductive traits in maiden rabbit does.
por: Salem, Anas A., et al.
Publicado: (2020)

Production of a Fungal Punicalagin-Degrading Enzyme by Solid-State Fermentation: Studies of Purification and Characterization
por: Aguilar-Zárate, Pedro, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vqchapalog1j7gjbt87rq17de9