Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach

Mutations can be important biomarkers that influence the selection of specific cancer treatments. We recently combined mathematical modeling of RAS signaling network biochemistry with experimental cancer cell biology to determine why KRAS G13D is a biomarker for sensitivity to epidermal growth facto...

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Detalles Bibliográficos
Autores principales: McFall, Thomas, Stites, Edward C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867612/
https://www.ncbi.nlm.nih.gov/pubmed/34910921
http://dx.doi.org/10.1016/j.celrep.2021.110096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867612/
https://www.ncbi.nlm.nih.gov/pubmed/34910921
http://dx.doi.org/10.1016/j.celrep.2021.110096

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