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Integration of liquid biopsy and pharmacogenomics for precision therapy of EGFR mutant and resistant lung cancers
The advent of molecular profiling has revolutionized the treatment of lung cancer by comprehensively delineating the genomic landscape of the epidermal growth factor receptor (EGFR) gene. Drug resistance caused by EGFR mutations and genetic polymorphisms of drug metabolizing enzymes and transporters...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867675/ https://www.ncbi.nlm.nih.gov/pubmed/35209919 http://dx.doi.org/10.1186/s12943-022-01534-8 |