Cargando…

Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects

AIM: Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthov...

Descripción completa

Detalles Bibliográficos
Autores principales: Djiepmo, Freddy, Tamaskovics, Bálint, Bölke, Edwin, Peiper, Matthias, Haussmann, Jan, Neuwahl, Judith, Jazmati, Danny, Maas, Kitti, Schmidt, Livia, Gelzhäuser, Roman, Schleich, Christoph, Corradini, Stefanie, Orth, Klaus, van Griensven, Martijn, Rezazadeh, Amir, Karimi, Kimia, Budach, Wilfried, Matuschek, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867737/
https://www.ncbi.nlm.nih.gov/pubmed/35197107
http://dx.doi.org/10.1186/s40001-022-00642-x
_version_ 1784656116040335360
author Djiepmo, Freddy
Tamaskovics, Bálint
Bölke, Edwin
Peiper, Matthias
Haussmann, Jan
Neuwahl, Judith
Jazmati, Danny
Maas, Kitti
Schmidt, Livia
Gelzhäuser, Roman
Schleich, Christoph
Corradini, Stefanie
Orth, Klaus
van Griensven, Martijn
Rezazadeh, Amir
Karimi, Kimia
Budach, Wilfried
Matuschek, Christiane
author_facet Djiepmo, Freddy
Tamaskovics, Bálint
Bölke, Edwin
Peiper, Matthias
Haussmann, Jan
Neuwahl, Judith
Jazmati, Danny
Maas, Kitti
Schmidt, Livia
Gelzhäuser, Roman
Schleich, Christoph
Corradini, Stefanie
Orth, Klaus
van Griensven, Martijn
Rezazadeh, Amir
Karimi, Kimia
Budach, Wilfried
Matuschek, Christiane
author_sort Djiepmo, Freddy
collection PubMed
description AIM: Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition. METHODS: We identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years. RESULTS: Before radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment. CONCLUSION: Radiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.
format Online
Article
Text
id pubmed-8867737
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-88677372022-02-25 Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects Djiepmo, Freddy Tamaskovics, Bálint Bölke, Edwin Peiper, Matthias Haussmann, Jan Neuwahl, Judith Jazmati, Danny Maas, Kitti Schmidt, Livia Gelzhäuser, Roman Schleich, Christoph Corradini, Stefanie Orth, Klaus van Griensven, Martijn Rezazadeh, Amir Karimi, Kimia Budach, Wilfried Matuschek, Christiane Eur J Med Res Research AIM: Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition. METHODS: We identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years. RESULTS: Before radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment. CONCLUSION: Radiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction. BioMed Central 2022-02-23 /pmc/articles/PMC8867737/ /pubmed/35197107 http://dx.doi.org/10.1186/s40001-022-00642-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Djiepmo, Freddy
Tamaskovics, Bálint
Bölke, Edwin
Peiper, Matthias
Haussmann, Jan
Neuwahl, Judith
Jazmati, Danny
Maas, Kitti
Schmidt, Livia
Gelzhäuser, Roman
Schleich, Christoph
Corradini, Stefanie
Orth, Klaus
van Griensven, Martijn
Rezazadeh, Amir
Karimi, Kimia
Budach, Wilfried
Matuschek, Christiane
Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
title Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
title_full Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
title_fullStr Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
title_full_unstemmed Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
title_short Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
title_sort low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867737/
https://www.ncbi.nlm.nih.gov/pubmed/35197107
http://dx.doi.org/10.1186/s40001-022-00642-x
work_keys_str_mv AT djiepmofreddy lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT tamaskovicsbalint lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT bolkeedwin lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT peipermatthias lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT haussmannjan lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT neuwahljudith lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT jazmatidanny lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT maaskitti lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT schmidtlivia lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT gelzhauserroman lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT schleichchristoph lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT corradinistefanie lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT orthklaus lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT vangriensvenmartijn lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT rezazadehamir lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT karimikimia lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT budachwilfried lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects
AT matuschekchristiane lowdoseradiationtreatmentforpainfulplantarenthesophyteahighlyeffectivetherapywithlittlesideeffects