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Calotropis Gigantea Fiber—A Biogenic Reinforcement Material for Europium Substituted Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary Composite for Biomedical Applications
[Image: see text] Novel multifunctional biocomposite materials that mimic the properties of bone are the need of the hour. In view of this, the current work is focused on the fabrication of a snail shells derived europium-substituted hydroxyapatite (Eu-HAP)/poly(3,4-propylenedioxythiophene) (PProDOT...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867816/ https://www.ncbi.nlm.nih.gov/pubmed/35224363 http://dx.doi.org/10.1021/acsomega.1c06372 |
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author | Raji, Ramachandran Elangomannan, Shinyjoy Subramani, Ramya Louis, Kavitha Periasamy, Manoravi Dhanaraj, Gopi |
author_facet | Raji, Ramachandran Elangomannan, Shinyjoy Subramani, Ramya Louis, Kavitha Periasamy, Manoravi Dhanaraj, Gopi |
author_sort | Raji, Ramachandran |
collection | PubMed |
description | [Image: see text] Novel multifunctional biocomposite materials that mimic the properties of bone are the need of the hour. In view of this, the current work is focused on the fabrication of a snail shells derived europium-substituted hydroxyapatite (Eu-HAP)/poly(3,4-propylenedioxythiophene) (PProDOT)/Calotropis gigantea fiber (CGF) ternary composite on titanium (Ti) for biomedical applications. The structural, morphological, mechanical, electrochemical, and biological properties of the as-developed coatings on Ti were characterized. The obtained results clearly confirmed the formation and properties of the ternary composite (Eu-HAP/PProDOT/CGF). The presence of CGF, an exceptional reinforcement material, in the ternary composite is proven to improve mechanical and biological properties compared to other coatings (i.e., coating without CGF). Also, electrochemical studies revealed better anticorrosion properties of the composite-coated Ti in a simulated body fluid (SBF) solution. Similarly, the presence of Eu-HAP and PProDOT in the composite is clearly evident from the antibacterial activity against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and also by the cell proliferation and cell adhesion by the MTT assay test. Thus, we suggest that the fabricated Eu-HAP/PProDOT/CGF ternary composite with mechanical, corrosion resistance, and biocompatible properties might be an appropriate candidate for biomedical applications. |
format | Online Article Text |
id | pubmed-8867816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-88678162022-02-25 Calotropis Gigantea Fiber—A Biogenic Reinforcement Material for Europium Substituted Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary Composite for Biomedical Applications Raji, Ramachandran Elangomannan, Shinyjoy Subramani, Ramya Louis, Kavitha Periasamy, Manoravi Dhanaraj, Gopi ACS Omega [Image: see text] Novel multifunctional biocomposite materials that mimic the properties of bone are the need of the hour. In view of this, the current work is focused on the fabrication of a snail shells derived europium-substituted hydroxyapatite (Eu-HAP)/poly(3,4-propylenedioxythiophene) (PProDOT)/Calotropis gigantea fiber (CGF) ternary composite on titanium (Ti) for biomedical applications. The structural, morphological, mechanical, electrochemical, and biological properties of the as-developed coatings on Ti were characterized. The obtained results clearly confirmed the formation and properties of the ternary composite (Eu-HAP/PProDOT/CGF). The presence of CGF, an exceptional reinforcement material, in the ternary composite is proven to improve mechanical and biological properties compared to other coatings (i.e., coating without CGF). Also, electrochemical studies revealed better anticorrosion properties of the composite-coated Ti in a simulated body fluid (SBF) solution. Similarly, the presence of Eu-HAP and PProDOT in the composite is clearly evident from the antibacterial activity against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and also by the cell proliferation and cell adhesion by the MTT assay test. Thus, we suggest that the fabricated Eu-HAP/PProDOT/CGF ternary composite with mechanical, corrosion resistance, and biocompatible properties might be an appropriate candidate for biomedical applications. American Chemical Society 2022-02-10 /pmc/articles/PMC8867816/ /pubmed/35224363 http://dx.doi.org/10.1021/acsomega.1c06372 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Raji, Ramachandran Elangomannan, Shinyjoy Subramani, Ramya Louis, Kavitha Periasamy, Manoravi Dhanaraj, Gopi Calotropis Gigantea Fiber—A Biogenic Reinforcement Material for Europium Substituted Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary Composite for Biomedical Applications |
title | Calotropis Gigantea Fiber—A
Biogenic Reinforcement Material for Europium Substituted
Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary
Composite for Biomedical Applications |
title_full | Calotropis Gigantea Fiber—A
Biogenic Reinforcement Material for Europium Substituted
Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary
Composite for Biomedical Applications |
title_fullStr | Calotropis Gigantea Fiber—A
Biogenic Reinforcement Material for Europium Substituted
Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary
Composite for Biomedical Applications |
title_full_unstemmed | Calotropis Gigantea Fiber—A
Biogenic Reinforcement Material for Europium Substituted
Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary
Composite for Biomedical Applications |
title_short | Calotropis Gigantea Fiber—A
Biogenic Reinforcement Material for Europium Substituted
Hydroxyapatite/Poly(3,4-propylenedioxythiophene) Matrix: A Novel Ternary
Composite for Biomedical Applications |
title_sort | calotropis gigantea fiber—a
biogenic reinforcement material for europium substituted
hydroxyapatite/poly(3,4-propylenedioxythiophene) matrix: a novel ternary
composite for biomedical applications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867816/ https://www.ncbi.nlm.nih.gov/pubmed/35224363 http://dx.doi.org/10.1021/acsomega.1c06372 |
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