Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson’s disease

BACKGROUND: Epidemiological studies suggest a link between the melanoma-related pigmentation gene melanocortin 1 receptor (MC1R) and risk of Parkinson’s disease (PD). We previously showed that MC1R signaling can facilitate nigrostriatal dopaminergic neuron survival. The present study investigates th...

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Detalles Bibliográficos
Autores principales: Cai, Waijiao, Srivastava, Pranay, Feng, Danielle, Lin, Yue, Vanderburg, Charles R., Xu, Yuehang, Mclean, Pamela, Frosch, Matthew P., Fisher, David E., Schwarzschild, Michael A., Chen, Xiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867846/
https://www.ncbi.nlm.nih.gov/pubmed/35197079
http://dx.doi.org/10.1186/s13024-022-00520-4

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