Repurposing the FDA‐approved anticancer agent ponatinib as a fluconazole potentiator by suppression of multidrug efflux and Pma1 expression in a broad spectrum of yeast species

Fungal infections have emerged as a major global threat to human health because of the increasing incidence and mortality rates every year. The emergence of drug resistance and limited arsenal of antifungal agents further aggravates the current situation resulting in a growing challenge in medical m...

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Detalles Bibliográficos
Autores principales: Liu, Lin, Jiang, Tong, Zhou, Jia, Mei, Yikun, Li, Jinyang, Tan, Jingcong, Wei, Luqi, Li, Jingquan, Peng, Yibing, Chen, Changbin, Liu, Ning‐Ning, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867973/
https://www.ncbi.nlm.nih.gov/pubmed/33955652
http://dx.doi.org/10.1111/1751-7915.13814

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