Cargando…

Dorsal Raphe 5-HT Neurons Utilize, But Do Not Generate, Negative Aversive Prediction Errors

The dorsal raphe nucleus (DRN) contains the largest population of serotonin (5-HT) neurons in the central nervous system. 5-HT, synthesized via tryptophan hydroxylase 2 (Tph2), is a widely functioning neuromodulator implicated in fear learning. Here, we sought to investigate whether DRN 5-HT is nece...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walker, Rachel A., Suthard, Rebecca L., Perison, Taylor N., Sheehan, Nora M., Dwyer, Caitlin C., Lee, Jillian K., Enabulele, Eghosa K., Ray, Madelyn H., McDannald, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2022
Materias:	Research Article: New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868025/ https://www.ncbi.nlm.nih.gov/pubmed/35078807 http://dx.doi.org/10.1523/ENEURO.0132-21.2022

Ejemplares similares

Early adolescent adversity alters periaqueductal gray/dorsal raphe threat responding in adult female rats
por: Moaddab, Mahsa, et al.
Publicado: (2020)

Early adversity disrupts the adult use of aversive prediction errors to reduce fear in uncertainty
por: Wright, Kristina M., et al.
Publicado: (2015)

The Role of Dorsal Raphe Serotonin Neurons in the Balance between Reward and Aversion
por: Nagai, Yuma, et al.
Publicado: (2020)

Reward processing by the dorsal raphe nucleus: 5-HT and beyond
por: Luo, Minmin, et al.
Publicado: (2015)

Lateral orbitofrontal cortex partitions mechanisms for fear regulation and alcohol consumption
por: Ray, Madelyn H., et al.
Publicado: (2018)

Ventral pallidum neurons dynamically signal relative threat
por: Moaddab, Mahsa, et al.
Publicado: (2021)

Adolescent Alcohol Drinking Renders Adult Drinking BLA-Dependent: BLA Hyper-Activity as Contributor to Comorbid Alcohol Use Disorder and Anxiety Disorders
por: Moaddab, Mahsa, et al.
Publicado: (2017)

Brainstem networks construct threat probability and prediction error from neuronal building blocks
por: Strickland, Jasmin A., et al.
Publicado: (2022)

The Dorsal Raphe Regulates the Duration of Attack through the Medial Orbitofrontal Cortex and Medial Amygdala
por: Nordman, Jacob, et al.
Publicado: (2020)

Electrophysiological Assessment of Serotonin and GABA Neuron Function in the Dorsal Raphe during the Third Trimester Equivalent Developmental Period in Mice123
por: Morton, Russell A., et al.
Publicado: (2016)

Pharmacological Characterization of 5-HT(1A) Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons
por: Montalbano, Alberto, et al.
Publicado: (2015)

Histochemical Characterization of the Dorsal Raphe-Periaqueductal Grey Dopamine Transporter Neurons Projecting to the Extended Amygdala
por: Zhao, Qin, et al.
Publicado: (2022)

GluA2-Lacking AMPA Receptors and Nitric Oxide Signaling Gate Spike-Timing–Dependent Potentiation of Glutamate Synapses in the Dorsal Raphe Nucleus
por: Haj-Dahmane, Samir, et al.
Publicado: (2017)

Lurasidone Sub-Chronically Activates Serotonergic Transmission via Desensitization of 5-HT1A and 5-HT7 Receptors in Dorsal Raphe Nucleus
por: Okada, Motohiro, et al.
Publicado: (2019)

5-HT(7) receptor modulates GABAergic transmission in the rat dorsal raphe nucleus and controls cortical release of serotonin
por: Kusek, Magdalena, et al.
Publicado: (2015)

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain
por: Forero, Andrea, et al.
Publicado: (2017)

5-HT in the dorsal raphe nucleus is involved in the effects of 100-Hz electro-acupuncture on the pain-depression dyad in rats
por: Wu, Yuan-Yuan, et al.
Publicado: (2017)

Interaction between estradiol and 5-HT(1A) receptors in the median raphe nucleus on acquisition of aversive information and association to the context in ovariectomized rats
por: Andrade, Telma Gonçalves Carneiro Spera de, et al.
Publicado: (2017)

Molecular and anatomical organization of the dorsal raphe nucleus
por: Huang, Kee Wui, et al.
Publicado: (2019)

Dorsal Raphe Dopamine Neurons Represent the Experience of Social Isolation
por: Matthews, Gillian A., et al.
Publicado: (2016)

Neural Circuit in the Dorsal Raphe Nucleus Responsible for Cannabinoid-Mediated Increases in 5-HT Efflux in the Nucleus Accumbens of the Rat Brain
por: Tao, Rui, et al.
Publicado: (2012)

Nesfatin-1 in the dorsal raphe nucleus influences visceral sensitivity via 5-HT neurons in male maternally separated rats
por: Zhang, Hui-Ai, et al.
Publicado: (2018)

Correction for Ielpo et al., GABAergic miR-34a regulates Dorsal Raphè inhibitory transmission in response to aversive, but not rewarding, stimuli
Publicado: (2023)

Sex-Specific Role for Dopamine Receptor D2 in Dorsal Raphe Serotonergic Neuron Modulation of Defensive Acoustic Startle and Dominance Behavior
por: Lyon, Krissy A., et al.
Publicado: (2020)

Median raphe serotonergic neurons projecting to the interpeduncular nucleus control preference and aversion
por: Kawai, Hiroyuki, et al.
Publicado: (2022)

The role of the dorsal raphé nucleus in reward-seeking behavior
por: Nakamura, Kae
Publicado: (2013)

The Role of GABA in the Dorsal Striatum-Raphe Nucleus Circuit Regulating Stress Vulnerability in Male Mice with High Levels of Shati/Nat8l
por: Miyanishi, Hajime, et al.
Publicado: (2023)

EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain
por: Teng, Teng, et al.
Publicado: (2017)

An Aversive Response to Osmotic Upshift in Caenorhabditis elegans
por: Yu, Jingyi, et al.
Publicado: (2017)

The 5-HT(7) receptor antagonist SB 269970 ameliorates corticosterone-induced alterations in 5-HT(7) receptor-mediated modulation of GABAergic transmission in the rat dorsal raphe nucleus
por: Sowa, Joanna, et al.
Publicado: (2018)

Electrophysiological and pharmacological properties of GABAergic cells in the dorsal raphe nucleus
por: Gocho, Yoshihiro, et al.
Publicado: (2012)

Serotonin neurons in the dorsal raphe nucleus encode reward signals
por: Li, Yi, et al.
Publicado: (2016)

Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
por: Kaur, Satvinder, et al.
Publicado: (2020)

Electrophysiological Characteristics of Dorsal Raphe Nucleus in Tail Suspension Test
por: Zhou, Liuchang, et al.
Publicado: (2022)

Maturation of glutamatergic transmission onto dorsal raphe serotonergic neurons
por: Kisner, Alexandre, et al.
Publicado: (2023)

Pyramidal Neurons in Rat Prefrontal Cortex Projecting to Ventral Tegmental Area and Dorsal Raphe Nucleus Express 5-HT(2A) Receptors
por: Vázquez-Borsetti, Pablo, et al.
Publicado: (2009)

Impact of the circadian nuclear receptor REV-ERBα in dorsal raphe 5-HT neurons on social interaction behavior, especially social preference
por: Jang, Sangwon, et al.
Publicado: (2023)

Roles for the Dorsal Striatum in Aversive Behavior
por: Stanley, Adrien T., et al.
Publicado: (2021)

Activation of a Habenulo–Raphe Circuit Is Critical for the Behavioral and Neurochemical Consequences of Uncontrollable Stress in the Male Rat
por: Dolzani, Samuel D., et al.
Publicado: (2016)

Ventrolateral periaqueductal gray neurons prioritize threat probability over fear output
por: Wright, Kristina M, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_egbehq3rjl2ha9n6l883uqgr7g