Cargando…

Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study

The assumed link between high levels of antimicrobial use on farms and selection for antimicrobial-resistant (AMR) bacteria on that farm remains difficult to prove. In the pilot study presented here, we analysed total antimicrobial use on 50 dairy farms in Austria and also collected environmental sa...

Descripción completa

Detalles Bibliográficos
Autores principales: Firth, Clair L., Käsbohrer, Annemarie, Pless, Peter, Koeberl-Jelovcan, Sandra, Obritzhauser, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868072/
https://www.ncbi.nlm.nih.gov/pubmed/35203728
http://dx.doi.org/10.3390/antibiotics11020124
_version_ 1784656176463478784
author Firth, Clair L.
Käsbohrer, Annemarie
Pless, Peter
Koeberl-Jelovcan, Sandra
Obritzhauser, Walter
author_facet Firth, Clair L.
Käsbohrer, Annemarie
Pless, Peter
Koeberl-Jelovcan, Sandra
Obritzhauser, Walter
author_sort Firth, Clair L.
collection PubMed
description The assumed link between high levels of antimicrobial use on farms and selection for antimicrobial-resistant (AMR) bacteria on that farm remains difficult to prove. In the pilot study presented here, we analysed total antimicrobial use on 50 dairy farms in Austria and also collected environmental samples to ascertain whether specific AMR bacteria were present. Antimicrobial use (AMU) analysis was based on electronic veterinary treatment records over a one-year period. Faecal samples for the assessment of extended-spectrum beta-lactamase (ESBL)-producing E. coli were collected from cowsheds, calf pens, and youngstock housing areas, as well as dust samples from barns, to isolate methicillin-resistant Staphylococcus aureus (MRSA). Bacteriological cultures were carried out on selective agar. Farms were split into groups of 25 of the highest antimicrobial users and 25 of the lowest users. Overall, samples from 13/50 (26.0%) farms were found to be positive for the presence of ESBL-producing E. coli. Of these, eight farms were in the low user group and five were in the high user group. Only one farm was confirmed to harbour MRSA. Statistical analyses demonstrated that there was no significant difference in this study population between high or low antimicrobial use with respect to the presence of ESBL-producing E. coli on farms (p = 0.33). In conclusion, the presence of specific AMR bacteria on farms in this study population was not found to have a statistically proven relationship with their level of antimicrobial use.
format Online
Article
Text
id pubmed-8868072
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-88680722022-02-25 Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study Firth, Clair L. Käsbohrer, Annemarie Pless, Peter Koeberl-Jelovcan, Sandra Obritzhauser, Walter Antibiotics (Basel) Article The assumed link between high levels of antimicrobial use on farms and selection for antimicrobial-resistant (AMR) bacteria on that farm remains difficult to prove. In the pilot study presented here, we analysed total antimicrobial use on 50 dairy farms in Austria and also collected environmental samples to ascertain whether specific AMR bacteria were present. Antimicrobial use (AMU) analysis was based on electronic veterinary treatment records over a one-year period. Faecal samples for the assessment of extended-spectrum beta-lactamase (ESBL)-producing E. coli were collected from cowsheds, calf pens, and youngstock housing areas, as well as dust samples from barns, to isolate methicillin-resistant Staphylococcus aureus (MRSA). Bacteriological cultures were carried out on selective agar. Farms were split into groups of 25 of the highest antimicrobial users and 25 of the lowest users. Overall, samples from 13/50 (26.0%) farms were found to be positive for the presence of ESBL-producing E. coli. Of these, eight farms were in the low user group and five were in the high user group. Only one farm was confirmed to harbour MRSA. Statistical analyses demonstrated that there was no significant difference in this study population between high or low antimicrobial use with respect to the presence of ESBL-producing E. coli on farms (p = 0.33). In conclusion, the presence of specific AMR bacteria on farms in this study population was not found to have a statistically proven relationship with their level of antimicrobial use. MDPI 2022-01-18 /pmc/articles/PMC8868072/ /pubmed/35203728 http://dx.doi.org/10.3390/antibiotics11020124 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Firth, Clair L.
Käsbohrer, Annemarie
Pless, Peter
Koeberl-Jelovcan, Sandra
Obritzhauser, Walter
Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study
title Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study
title_full Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study
title_fullStr Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study
title_full_unstemmed Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study
title_short Analysis of Antimicrobial Use and the Presence of Antimicrobial-Resistant Bacteria on Austrian Dairy Farms—A Pilot Study
title_sort analysis of antimicrobial use and the presence of antimicrobial-resistant bacteria on austrian dairy farms—a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868072/
https://www.ncbi.nlm.nih.gov/pubmed/35203728
http://dx.doi.org/10.3390/antibiotics11020124
work_keys_str_mv AT firthclairl analysisofantimicrobialuseandthepresenceofantimicrobialresistantbacteriaonaustriandairyfarmsapilotstudy
AT kasbohrerannemarie analysisofantimicrobialuseandthepresenceofantimicrobialresistantbacteriaonaustriandairyfarmsapilotstudy
AT plesspeter analysisofantimicrobialuseandthepresenceofantimicrobialresistantbacteriaonaustriandairyfarmsapilotstudy
AT koeberljelovcansandra analysisofantimicrobialuseandthepresenceofantimicrobialresistantbacteriaonaustriandairyfarmsapilotstudy
AT obritzhauserwalter analysisofantimicrobialuseandthepresenceofantimicrobialresistantbacteriaonaustriandairyfarmsapilotstudy