Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

Kynurenine 3-monooxygenase (KMO), a key player in the kynurenine pathway (KP) of tryptophan degradation, regulates the synthesis of the neuroactive metabolites 3-hydroxykynurenine (3-HK) and kynurenic acid (KYNA). KMO activity has been implicated in several major brain diseases including Huntington’...

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Detalles Bibliográficos
Autores principales: Sathyasaikumar, Korrapati V., Pérez de la Cruz, Verónica, Pineda, Benjamín, Vázquez Cervantes, Gustavo Ignacio, Ramírez Ortega, Daniela, Donley, David W., Severson, Paul L., West, Brian L., Giorgini, Flaviano, Fox, Jonathan H., Schwarcz, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868204/
https://www.ncbi.nlm.nih.gov/pubmed/35204197
http://dx.doi.org/10.3390/antiox11020315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868204/
https://www.ncbi.nlm.nih.gov/pubmed/35204197
http://dx.doi.org/10.3390/antiox11020315

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