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Effect of Artemisinin on the Redox System of NADPH/FNR/Ferredoxin from Malaria Parasites

FNR and ferredoxin constitute a redox cascade, which provides reducing power in the plastid of malaria parasites. Recently, mutation of ferredoxin (D97Y) was reported to be strongly related to the parasite’s resistance to the front-line antimalarial drug artemisinin. In order to gain insight into th...

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Detalles Bibliográficos
Autores principales: Kimata-Ariga, Yoko, Morihisa, Rena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868210/
https://www.ncbi.nlm.nih.gov/pubmed/35204156
http://dx.doi.org/10.3390/antiox11020273