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Clostridioides Difficile Enteritis: Case Report and Literature Review

Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis. However, there have been reports of infectious enteritis mainly in patients with ileostomy, causing dehydration through high-output volume; Case presen...

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Autores principales: Klimko, Artsiom, Tieranu, Cristian George, Curte, Ana-Maria, Preda, Carmen Monica, Tieranu, Ioana, Olteanu, Andrei Ovidiu, Ionescu, Elena Mirela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868300/
https://www.ncbi.nlm.nih.gov/pubmed/35203809
http://dx.doi.org/10.3390/antibiotics11020206
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author Klimko, Artsiom
Tieranu, Cristian George
Curte, Ana-Maria
Preda, Carmen Monica
Tieranu, Ioana
Olteanu, Andrei Ovidiu
Ionescu, Elena Mirela
author_facet Klimko, Artsiom
Tieranu, Cristian George
Curte, Ana-Maria
Preda, Carmen Monica
Tieranu, Ioana
Olteanu, Andrei Ovidiu
Ionescu, Elena Mirela
author_sort Klimko, Artsiom
collection PubMed
description Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis. However, there have been reports of infectious enteritis mainly in patients with ileostomy, causing dehydration through high-output volume; Case presentation: We report the case of a 46-year-old male patient, malnourished, who presented with high-output ileostomy following a recent hospitalization where he had suffered an ileo-colic resection with ileal and transverse colon double ostomy, for stricturing Crohn’s disease. Clostridioides Difficile toxin A was identified in the ileal output confirming the diagnosis of acute enteritis. Treatment with oral Vancomycin was initiated with rapid reduction of the ileostomy output volume; Conclusion: We report a case of Clostridioides Difficile enteral infection as a cause for high-output ileostomy, successfully treated with oral Vancomycin. We also review the existing literature data regarding this specific localized infection.
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spelling pubmed-88683002022-02-25 Clostridioides Difficile Enteritis: Case Report and Literature Review Klimko, Artsiom Tieranu, Cristian George Curte, Ana-Maria Preda, Carmen Monica Tieranu, Ioana Olteanu, Andrei Ovidiu Ionescu, Elena Mirela Antibiotics (Basel) Review Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis. However, there have been reports of infectious enteritis mainly in patients with ileostomy, causing dehydration through high-output volume; Case presentation: We report the case of a 46-year-old male patient, malnourished, who presented with high-output ileostomy following a recent hospitalization where he had suffered an ileo-colic resection with ileal and transverse colon double ostomy, for stricturing Crohn’s disease. Clostridioides Difficile toxin A was identified in the ileal output confirming the diagnosis of acute enteritis. Treatment with oral Vancomycin was initiated with rapid reduction of the ileostomy output volume; Conclusion: We report a case of Clostridioides Difficile enteral infection as a cause for high-output ileostomy, successfully treated with oral Vancomycin. We also review the existing literature data regarding this specific localized infection. MDPI 2022-02-06 /pmc/articles/PMC8868300/ /pubmed/35203809 http://dx.doi.org/10.3390/antibiotics11020206 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Klimko, Artsiom
Tieranu, Cristian George
Curte, Ana-Maria
Preda, Carmen Monica
Tieranu, Ioana
Olteanu, Andrei Ovidiu
Ionescu, Elena Mirela
Clostridioides Difficile Enteritis: Case Report and Literature Review
title Clostridioides Difficile Enteritis: Case Report and Literature Review
title_full Clostridioides Difficile Enteritis: Case Report and Literature Review
title_fullStr Clostridioides Difficile Enteritis: Case Report and Literature Review
title_full_unstemmed Clostridioides Difficile Enteritis: Case Report and Literature Review
title_short Clostridioides Difficile Enteritis: Case Report and Literature Review
title_sort clostridioides difficile enteritis: case report and literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868300/
https://www.ncbi.nlm.nih.gov/pubmed/35203809
http://dx.doi.org/10.3390/antibiotics11020206
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