Systemic Effects of mitoTEMPO upon Lipopolysaccharide Challenge Are Due to Its Antioxidant Part, While Local Effects in the Lung Are Due to Triphenylphosphonium

Mitochondria-targeted antioxidants (mtAOX) are a promising treatment strategy against reactive oxygen species-induced damage. Reports about harmful effects of mtAOX lead to the question of whether these could be caused by the carrier molecule triphenylphosphonium (TPP). The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Weidinger, Adelheid, Birgisdóttir, Linda, Schäffer, Julia, Meszaros, Andras T., Zavadskis, Sergejs, Müllebner, Andrea, Hecker, Matthias, Duvigneau, Johanna Catharina, Sommer, Natascha, Kozlov, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868379/
https://www.ncbi.nlm.nih.gov/pubmed/35204206
http://dx.doi.org/10.3390/antiox11020323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868379/
https://www.ncbi.nlm.nih.gov/pubmed/35204206
http://dx.doi.org/10.3390/antiox11020323

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