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Systemic Effects of mitoTEMPO upon Lipopolysaccharide Challenge Are Due to Its Antioxidant Part, While Local Effects in the Lung Are Due to Triphenylphosphonium
Mitochondria-targeted antioxidants (mtAOX) are a promising treatment strategy against reactive oxygen species-induced damage. Reports about harmful effects of mtAOX lead to the question of whether these could be caused by the carrier molecule triphenylphosphonium (TPP). The aim of this study was to...
Autores principales: | Weidinger, Adelheid, Birgisdóttir, Linda, Schäffer, Julia, Meszaros, Andras T., Zavadskis, Sergejs, Müllebner, Andrea, Hecker, Matthias, Duvigneau, Johanna Catharina, Sommer, Natascha, Kozlov, Andrey V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868379/ https://www.ncbi.nlm.nih.gov/pubmed/35204206 http://dx.doi.org/10.3390/antiox11020323 |
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