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Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives

Regarded as one of the best solutions to replace missing teeth in the oral cavity, dental implants have been the focus of plenty of studies and research in the past few years. Antimicrobial coatings are a promising solution to control and prevent bacterial infections that compromise the success of d...

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Autores principales: Esteves, Guilherme Melo, Esteves, João, Resende, Marta, Mendes, Luzia, Azevedo, Andreia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868456/
https://www.ncbi.nlm.nih.gov/pubmed/35203837
http://dx.doi.org/10.3390/antibiotics11020235
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author Esteves, Guilherme Melo
Esteves, João
Resende, Marta
Mendes, Luzia
Azevedo, Andreia S.
author_facet Esteves, Guilherme Melo
Esteves, João
Resende, Marta
Mendes, Luzia
Azevedo, Andreia S.
author_sort Esteves, Guilherme Melo
collection PubMed
description Regarded as one of the best solutions to replace missing teeth in the oral cavity, dental implants have been the focus of plenty of studies and research in the past few years. Antimicrobial coatings are a promising solution to control and prevent bacterial infections that compromise the success of dental implants. In the last few years, new materials that prevent biofilm adhesion to the surface of titanium implants have been reported, ranging from improved methods to already established coating surfaces. The purpose of this review is to present the developed antimicrobial and antibiofilm coatings that may have the potential to reduce bacterial infections and improve the success rate of titanium dental implants. All referred coating surfaces showed high antimicrobial properties with effectiveness in biofilm control, while maintaining implant biocompatibility. We expect that by combining the use of oligonucleotide probes as a covering material with novel peri-implant adjuvant therapies, we will be able to avoid the downsides of other covering materials (such as antibiotic resistance), prevent bacterial infections, and raise the success rate of dental implants. The existing knowledge on the optimal coating material for dental implants is limited, and further research is needed before more definitive conclusions can be drawn.
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spelling pubmed-88684562022-02-25 Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives Esteves, Guilherme Melo Esteves, João Resende, Marta Mendes, Luzia Azevedo, Andreia S. Antibiotics (Basel) Review Regarded as one of the best solutions to replace missing teeth in the oral cavity, dental implants have been the focus of plenty of studies and research in the past few years. Antimicrobial coatings are a promising solution to control and prevent bacterial infections that compromise the success of dental implants. In the last few years, new materials that prevent biofilm adhesion to the surface of titanium implants have been reported, ranging from improved methods to already established coating surfaces. The purpose of this review is to present the developed antimicrobial and antibiofilm coatings that may have the potential to reduce bacterial infections and improve the success rate of titanium dental implants. All referred coating surfaces showed high antimicrobial properties with effectiveness in biofilm control, while maintaining implant biocompatibility. We expect that by combining the use of oligonucleotide probes as a covering material with novel peri-implant adjuvant therapies, we will be able to avoid the downsides of other covering materials (such as antibiotic resistance), prevent bacterial infections, and raise the success rate of dental implants. The existing knowledge on the optimal coating material for dental implants is limited, and further research is needed before more definitive conclusions can be drawn. MDPI 2022-02-11 /pmc/articles/PMC8868456/ /pubmed/35203837 http://dx.doi.org/10.3390/antibiotics11020235 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Esteves, Guilherme Melo
Esteves, João
Resende, Marta
Mendes, Luzia
Azevedo, Andreia S.
Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives
title Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives
title_full Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives
title_fullStr Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives
title_full_unstemmed Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives
title_short Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives
title_sort antimicrobial and antibiofilm coating of dental implants—past and new perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868456/
https://www.ncbi.nlm.nih.gov/pubmed/35203837
http://dx.doi.org/10.3390/antibiotics11020235
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