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Metformin Reverses tmexCD1-toprJ1- and tet(A)-Mediated High-Level Tigecycline Resistance in K. pneumoniae

Tigecycline (TIG) is one of the last effective options against multidrug resistance bacteria. Recently, the RND (resistance–nodulation–division) efflux pump gene cluster, tmexCD1-toprJ1, and the tetracycline-efflux pump tet(A) mutation were reported to mediate high level resistance to TIG in clinica...

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Detalles Bibliográficos
Autores principales:	Xiao, Xia, Huan, Quanmin, Huang, Yanhu, Liu, Yuan, Li, Ruichao, Xu, Xilan, Wang, Zhiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868462/ https://www.ncbi.nlm.nih.gov/pubmed/35203765 http://dx.doi.org/10.3390/antibiotics11020162

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