Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca(2+)-Independent Phospholipase A(2)γ in the Brain

Mitochondrial Ca(2+)-independent phospholipase A(2)γ (iPLA(2)γ/PNPLA8) was previously shown to be directly activated by H(2)O(2) and release free fatty acids (FAs) for FA-dependent H(+) transport mediated by the adenine nucleotide translocase (ANT) or uncoupling protein 2 (UCP2). The resulting mild...

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Detalles Bibliográficos
Autores principales: Průchová, Pavla, Gotvaldová, Klára, Smolková, Katarína, Alán, Lukáš, Holendová, Blanka, Tauber, Jan, Galkin, Alexander, Ježek, Petr, Jabůrek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868467/
https://www.ncbi.nlm.nih.gov/pubmed/35204081
http://dx.doi.org/10.3390/antiox11020198

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