The Crosstalk between GPR81/IGFBP6 Promotes Breast Cancer Progression by Modulating Lactate Metabolism and Oxidative Stress

Breast cancer is the most frequent tumor and the leading cause of cancer deaths in women. In recent years, lactate metabolism and, in particular, its receptor GPR81 have been shown to play a vital role in cancer biology. GPR81 is upregulated in breast cancer and promotes tumor growth by tumor cell-d...

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Detalles Bibliográficos
Autores principales: Longhitano, Lucia, Forte, Stefano, Orlando, Laura, Grasso, Stephanie, Barbato, Alessandro, Vicario, Nunzio, Parenti, Rosalba, Fontana, Paolo, Amorini, Angela M., Lazzarino, Giuseppe, Li Volti, Giovanni, Di Rosa, Michelino, Liso, Arcangelo, Tavazzi, Barbara, Lazzarino, Giacomo, Tibullo, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868469/
https://www.ncbi.nlm.nih.gov/pubmed/35204157
http://dx.doi.org/10.3390/antiox11020275

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