Nrf2/ARE Signaling Directly Regulates SOX9 to Potentially Alter Age-Dependent Cartilage Degeneration

Oxidative stress is implicated in osteoarthritis, and nuclear factor erythroid 2–related factor 2 (Nrf2)/antioxidant response element (ARE) pathway maintains redox homeostasis. We investigated whether Nrf2/ARE signaling controls SOX9. SOX9 expression in human C-28/I2 chondrocytes was measured by RT–...

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Detalles Bibliográficos
Autores principales: Kubo, Yusuke, Beckmann, Rainer, Fragoulis, Athanassios, Conrads, Claudius, Pavanram, Prathyusha, Nebelung, Sven, Wolf, Michael, Wruck, Christoph Jan, Jahr, Holger, Pufe, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868513/
https://www.ncbi.nlm.nih.gov/pubmed/35204144
http://dx.doi.org/10.3390/antiox11020263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8868513/
https://www.ncbi.nlm.nih.gov/pubmed/35204144
http://dx.doi.org/10.3390/antiox11020263

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