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Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance

The use of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) as first-line treatment in patients with lung adenocarcinoma (LUAD) harboring EGFR-activating mutations has resulted in a dramatic improvement in the management of the disease. However, the long-term clinical benefi...

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Detalles Bibliográficos
Autores principales:	Gkountakos, Anastasios, Centonze, Giovanni, Vita, Emanuele, Belluomini, Lorenzo, Milella, Michele, Bria, Emilio, Milione, Massimo, Scarpa, Aldo, Simbolo, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869286/ https://www.ncbi.nlm.nih.gov/pubmed/35203491 http://dx.doi.org/10.3390/biomedicines10020277

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