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CAR-T Regulatory (CAR-Treg) Cells: Engineering and Applications

Regulatory T cells are critical for maintaining immune tolerance. Recent studies have confirmed their therapeutic suppressive potential to modulate immune responses in organ transplant and autoimmune diseases. However, the unknown and nonspecific antigen recognition of polyclonal Tregs has impaired...

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Detalles Bibliográficos
Autores principales: Arjomandnejad, Motahareh, Kopec, Acadia L., Keeler, Allison M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869296/
https://www.ncbi.nlm.nih.gov/pubmed/35203496
http://dx.doi.org/10.3390/biomedicines10020287