Cargando…

An Enzymatic Biosensor for the Detection of D-2-Hydroxyglutaric Acid in Serum and Urine

D-2-hydroxyglutaric acid (D2HG) is overproduced as a result of the D-2-hydroxyglutaric aciduria and relevant cancers, caused by gene mutation. Accurate analysis of D2HG could help rapid diagnosis of these diseases and allow for timely treatment. In this work, a D-2-hydroxyglutarate dehydrogenase fro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Bo, Li, Zehua, Kang, Zepeng, Ma, Chunling, Song, Haiyan, Lu, Fuping, Zhu, Zhiguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869338/ https://www.ncbi.nlm.nih.gov/pubmed/35200327 http://dx.doi.org/10.3390/bios12020066

Ejemplares similares

Urine 2-Hydroxyglutarate in Glioma
por: Lombardi, Giuseppe, et al.
Publicado: (2016)

A d-2-hydroxyglutarate biosensor based on specific transcriptional regulator DhdR
por: Xiao, Dan, et al.
Publicado: (2021)

An l-2-hydroxyglutarate biosensor based on specific transcriptional regulator LhgR
por: Kang, Zhaoqi, et al.
Publicado: (2021)

D-2-Hydroxyglutarate in Glioma Biology
por: Chou, Fu-Ju, et al.
Publicado: (2021)

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases
por: Tarhonskaya, Hanna, et al.
Publicado: (2014)

The Roles of 2-Hydroxyglutarate
por: Du, Xin, et al.
Publicado: (2021)

D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells
por: Ugele, Ines, et al.
Publicado: (2019)

Metabolism, Activity, and Targeting of D-and L-2-Hydroxyglutarates
por: Ye, Dan, et al.
Publicado: (2018)

D-2-Hydroxyglutaric Aciduria with Enchondromatosis and Angiokeratoma Circumscriptum
por: Preston, Allie, et al.
Publicado: (2019)

The sodium-dependent di- and tricarboxylate transporter, NaCT, is not responsible for the uptake of D-, L-2-hydroxyglutarate and 3-hydroxyglutarate into neurons
por: Brauburger, Katja, et al.
Publicado: (2011)

D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma
por: Pusch, Stefan, et al.
Publicado: (2014)

2-Hydroxyglutarate in Cancer Cells
por: Ježek, Petr
Publicado: (2020)

Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d-2-Hydroxyglutarate
por: Fan, Jing, et al.
Publicado: (2014)

Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations
por: Berger, Raffaela S., et al.
Publicado: (2019)

Non-Enzymatic Glucose Detection Based on NiS Nanoclusters@NiS Nanosphere in Human Serum and Urine
por: Arivazhagan, Mani, et al.
Publicado: (2021)

From Enzymatic Dopamine Biosensors to OECT Biosensors of Dopamine
por: Ravariu, Cristian
Publicado: (2023)

Wearable Enzymatic Alcohol Biosensor
por: Lansdorp, Bob, et al.
Publicado: (2019)

Laser-Induced Graphene-Based Enzymatic Biosensor for Glucose Detection
por: Settu, Kalpana, et al.
Publicado: (2021)

Progress in understanding 2-hydroxyglutaric acidurias
por: Kranendijk, Martijn, et al.
Publicado: (2012)

The effects of 2-hydroxyglutarate on the tumorigenesis of gliomas
por: Reiter-Brennan, Cara, et al.
Publicado: (2018)

Serum D‐2‐hydroxyglutarate and the ratio of D‐2HG/L‐2HG predict IDH mutation in acute myeloid leukemia
por: Zhang, Chelsea, et al.
Publicado: (2023)

Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer
por: Han, Jie, et al.
Publicado: (2018)

Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite
por: Berger, Raffaela S., et al.
Publicado: (2021)

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated glioma patients
por: Choi, Changho, et al.
Publicado: (2012)

Comparison of 2-Hydroxyglutarate Detection With sLASER and MEGA-sLASER at 7T
por: Shams, Zahra, et al.
Publicado: (2021)

Biosensors for D-Amino Acids: Detection Methods and Applications
por: Rosini, Elena, et al.
Publicado: (2020)

D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice
por: Akbay, Esra A., et al.
Publicado: (2014)

Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate and promotes histone methylation
por: Fan, Jing, et al.
Publicado: (2014)

The Emerging Role of D-2-Hydroxyglutarate as an Oncometabolite in Hematolymphoid and Central Nervous System Neoplasms
por: Rakheja, Dinesh, et al.
Publicado: (2013)

Child with D-2-Hydroxyglutaric Aciduria Type II: A Rare Neurometabolic Disorder
por: Srinivasaraghavan, Rangan, et al.
Publicado: (2021)

Improved Localization for 2-Hydroxyglutarate Detection at 3 T Using Long-TE Semi-LASER
por: Berrington, Adam, et al.
Publicado: (2016)

Magnetic Resonance Spectroscopy for Detection of 2-Hydroxyglutarate as a Biomarker for IDH Mutation in Gliomas
por: Leather, Thomas, et al.
Publicado: (2017)

L-2-hydroxyglutarate production arises from non-canonical enzyme function at acidic pH
por: Intlekofer, Andrew M., et al.
Publicado: (2017)

D‐2‐hydroxyglutaric aciduria Type I: Functional analysis of D2HGDH missense variants
por: Pop, Ana, et al.
Publicado: (2019)

Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney
por: Brinkley, Garrett, et al.
Publicado: (2020)

Biosensor and chemo-enzymatic one-pot cascade applications to detect and transform PET-derived terephthalic acid in living cells
por: Bayer, Thomas, et al.
Publicado: (2022)

Development of a Biosensor-Based Rapid Urine Test for Detection of Urogenital Schistosomiasis
por: Mach, Kathleen E., et al.
Publicado: (2015)

An electrochemical biosensor for the detection of Mycobacterium tuberculosis DNA from sputum and urine samples
por: Ramos-Sono, Daniel, et al.
Publicado: (2020)

A Novel Urine Test Biosensor Platform for Early Lung Cancer Detection
por: Wiesel, Ory, et al.
Publicado: (2023)

Studies on the Detection of Oleuropein from Extra Virgin Olive Oils Using Enzymatic Biosensors
por: Bounegru, Alexandra Virginia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gei8t3rjk8ufnrd01k2f3238e5