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Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings

More than 300 million people worldwide are diagnosed with a chronic hepatitis B virus (HBV) infection. Nucleos(t)ide viral polymerase inhibitors are available on the market and can efficiently treat patients with chronic HBV. However, life-long treatment is needed as covalently closed circular DNA (...

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Detalles Bibliográficos
Autores principales: Tricot, Tine, Thibaut, Hendrik Jan, Abbasi, Kayvan, Boon, Ruben, Helsen, Nicky, Kumar, Manoj, Neyts, Johan, Verfaillie, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869365/
https://www.ncbi.nlm.nih.gov/pubmed/35203482
http://dx.doi.org/10.3390/biomedicines10020268