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The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women
In both sexes, aggression has been described as a critical trait to acquire social status. Still, almost uniquely in men, the link between aggressiveness and the genetic background of testosterone sensitivity measured from the polymorphism in the androgen receptor (AR) gene has been previously inves...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869512/ https://www.ncbi.nlm.nih.gov/pubmed/35200293 http://dx.doi.org/10.3390/bs12020042 |
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author | Valenzuela, Nohelia T. Ruiz-Pérez, Irene Rodríguez-Sickert, Carlos Polo, Pablo Muñoz-Reyes, José Antonio Yeste-Lizán, Ali Pita, Miguel |
author_facet | Valenzuela, Nohelia T. Ruiz-Pérez, Irene Rodríguez-Sickert, Carlos Polo, Pablo Muñoz-Reyes, José Antonio Yeste-Lizán, Ali Pita, Miguel |
author_sort | Valenzuela, Nohelia T. |
collection | PubMed |
description | In both sexes, aggression has been described as a critical trait to acquire social status. Still, almost uniquely in men, the link between aggressiveness and the genetic background of testosterone sensitivity measured from the polymorphism in the androgen receptor (AR) gene has been previously investigated. We assessed the relevance of the AR gene to understand aggression and how aggressiveness affects social status in a cross-sectional study of 195 participants, for the first time in both young men and women. We estimated polymorphism sequences from saliva and measured aggression and self-perceived social status. Unfortunately, the results did not support our prediction because we did not find any of the expected relationships. Therefore, the results suggest that the genetic association between aggressive mechanisms and polymorphism of the AR gene is less straightforward than expected, at least in men, and seems to indicate that aggression is not usually used to gain social status in our population. |
format | Online Article Text |
id | pubmed-8869512 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88695122022-02-25 The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women Valenzuela, Nohelia T. Ruiz-Pérez, Irene Rodríguez-Sickert, Carlos Polo, Pablo Muñoz-Reyes, José Antonio Yeste-Lizán, Ali Pita, Miguel Behav Sci (Basel) Article In both sexes, aggression has been described as a critical trait to acquire social status. Still, almost uniquely in men, the link between aggressiveness and the genetic background of testosterone sensitivity measured from the polymorphism in the androgen receptor (AR) gene has been previously investigated. We assessed the relevance of the AR gene to understand aggression and how aggressiveness affects social status in a cross-sectional study of 195 participants, for the first time in both young men and women. We estimated polymorphism sequences from saliva and measured aggression and self-perceived social status. Unfortunately, the results did not support our prediction because we did not find any of the expected relationships. Therefore, the results suggest that the genetic association between aggressive mechanisms and polymorphism of the AR gene is less straightforward than expected, at least in men, and seems to indicate that aggression is not usually used to gain social status in our population. MDPI 2022-02-10 /pmc/articles/PMC8869512/ /pubmed/35200293 http://dx.doi.org/10.3390/bs12020042 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Valenzuela, Nohelia T. Ruiz-Pérez, Irene Rodríguez-Sickert, Carlos Polo, Pablo Muñoz-Reyes, José Antonio Yeste-Lizán, Ali Pita, Miguel The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women |
title | The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women |
title_full | The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women |
title_fullStr | The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women |
title_full_unstemmed | The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women |
title_short | The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women |
title_sort | relationship between androgen receptor gene polymorphism, aggression and social status in young men and women |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869512/ https://www.ncbi.nlm.nih.gov/pubmed/35200293 http://dx.doi.org/10.3390/bs12020042 |
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