CoenzymeQ10 and Ischemic Preconditioning Potentially Prevent Tourniquet-Induced Ischemia/Reperfusion in Knee Arthroplasty, but Combined Pretreatment Possibly Neutralizes Their Beneficial Effects

Tourniquet (TQ) use during total knee arthroplasty (TKA) induces ischemia/reperfusion (I/R) injury, resulting in mitochondrial dysfunction. This study aims to determine the effects of coenzyme Q10 (CoQ10) and ischemic preconditioning (IPC), either alone or in combination, on I/R-induced mitochondria...

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Detalles Bibliográficos
Autores principales: Leurcharusmee, Prangmalee, Sawaddiruk, Passakorn, Punjasawadwong, Yodying, Sugundhavesa, Nantawit, Klunklin, Kasisin, Tongprasert, Siam, Sitilertpisan, Patraporn, Jaiwongkam, Thidarat, Apaijai, Nattayaporn, Chattipakorn, Nipon, Chattipakorn, Siriporn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869537/
https://www.ncbi.nlm.nih.gov/pubmed/35204301
http://dx.doi.org/10.3390/antiox11020419

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